Abstract
Herpes simplex virus (HSV) was isolated from penile lesions of 15
college men. Using (E)-5-(2-bromovinyl)-2'-deoxyuridine sensitivity,
monoclonal antibody immunofluorescence, and restriction endonuclease
EcoRI digestion of viral DNA, 4 of 15 (26%) isolates were found to
be HSV-1, and 11 of 15 (74%) isolates were found to be HSV-2. It
is likely that some of the genital HSV-1 infections are related to
oral genital contact, but this fact could not be established for
all cases, since the females in this group had previously been shown
to have a high incidence of genital HSV-1.
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