Zusammenfassung
Depression is one of the most common mental health disorders. Acupuncture
is a popular complementary and alternative medicine intervention
suggested in the treatment of depression, but its effectiveness is
uncertain. This updated meta-analysis was conducted to more precisely
assess the beneficial effect of acupuncture in depression therapy.The
following databases were searched: MEDLINE, EMBASE, BIOSIS, Cochrane
Central Register of Controlled Trials, and Chinese Scientific Journal
Database. The following terms were used: acupuncture, acupressure,
depression, depressive disorder, clinical trial, and randomized controlled
trial.Eight small-randomized controlled trials comparing 477 subjects
were included in the meta-analysis. Our results confirmed that acupuncture
could significantly reduce the severity of depression, which was
indicated by decreased scores of Hamilton rating scale for depression
(HAMD) or Beck Depression Inventory (BDI). The pooled standardized
mean difference of the 'Improvement of depression' was -0.65 (95\%
CI -1.18, -0.11; P=0.02) by random effect model. However, no significant
effect of active acupuncture was found on the response rate (RR 1.32,
95\% CI 0.83 to 2.10; P=0.25) and remission rate (RR 1.30, 95\% CI
0.57 to 2.95; P=0.53).Although this meta-analysis might be discounted
due to the low quality of individual trials, it supported that acupuncture
was an effective treatment that could significantly reduce the severity
of disease in the patients with depression. More full-scale randomized
clinical trials with reliable designs are recommended to further
warrant the effectiveness of acupuncture.
Nutzer