%0 Journal Article %1 citeulike:637389 %A Smith, Richard S. %A Curtiss, Linda K. %A Koduri, Kanaka R. %A Witztum, Joseph L. %A Young, Stephen G. %C The Scripps Research Institute (La Jolla, CA) %D 1992 %J United States Patent %K mapping epitope apob %T Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides %V 5408038 %X Methods and compositions are described for determining the level of low density lipoproteins (LDL) in plasma. Native apoprotein B-100 (apo B-100) present in LDL particles is immunologically mimicked by a polypeptide of the invention. A polypeptide includes an amino acid residue sequence corresponding to a pan epitope region of the target apoprotein. A preferred polypeptide is a fusion protein that simultaneously mimics native apo B-100 and native apo A-I. Improved assay systems and methods for determining HDL and LDL levels in a body fluid sample are also described.

@article{citeulike:637389, abstract = {Methods and compositions are described for determining the level of low density lipoproteins (LDL) in plasma. Native apoprotein B-100 (apo B-100) present in LDL particles is immunologically mimicked by a polypeptide of the invention. A polypeptide includes an amino acid residue sequence corresponding to a pan epitope region of the target apoprotein. A preferred polypeptide is a fusion protein that simultaneously mimics native apo B-100 and native apo A-I. Improved assay systems and methods for determining HDL and LDL levels in a body fluid sample are also described.}, added-at = {2006-07-07T01:10:50.000+0200}, address = {The Scripps Research Institute (La Jolla, CA)}, author = {Smith, Richard S. and Curtiss, Linda K. and Koduri, Kanaka R. and Witztum, Joseph L. and Young, Stephen G.}, biburl = {https://www.bibsonomy.org/bibtex/216f2c62536318d9b84b42c794c026c5f/biblio24}, citeulike-article-id = {637389}, interhash = {9be6be678e41857a40b2614cfbb154be}, intrahash = {16f2c62536318d9b84b42c794c026c5f}, journal = {United States Patent}, keywords = {mapping epitope apob}, month = {October}, priority = {2}, timestamp = {2006-07-07T01:10:50.000+0200}, title = {Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides}, volume = 5408038, year = 1992 }