%0 Journal Article %1 Draget1997 %A Draget, K. I. %A Skjak-Braek, G. %A Smidsrod, O. %C PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS %D 1997 %I ELSEVIER SCIENCE BV %J Int. J. Biol. Macromol. %K ; ;; [ISI:] acid; alginates; azotobacter-vinelandii; chemical-composition; gels; islets polysaccharides residues; sequence; uronate %N 1-2 %P 47 -- 55 %T Alginate based new materials %V 21 %X Present and future applications of alginates are mainly linked to the most striking feature of the alginate molecule; i.e. a sol/gel transition in the presence of multivalent cations, e.g. Ca2+, almost independent on temperature. These very mild conditions, combined with the fact that alginates are highly characterised and understood both in the liquid and in the gel phase, makes this biopolymer unique compared to other gelling polysaccharides. Only pectins resemble alginate in the sol/gel transition behaviour, but this system can hardly be said to be as well characterised and understood as the alginates. The properties of alginate solutions and gels suggest biomedical and pharmaceutical uses. In this paper, the question of the specifications required by a polymer for applications in some biomedical areas will be discussed. (C) 1997 Elsevier Science B.V.

@article{Draget1997, __markedentry = {[phpts:6]}, abstract = {Present and future applications of alginates are mainly linked to the most striking feature of the alginate molecule; i.e. a sol/gel transition in the presence of multivalent cations, e.g. Ca2+, almost independent on temperature. These very mild conditions, combined with the fact that alginates are highly characterised and understood both in the liquid and in the gel phase, makes this biopolymer unique compared to other gelling polysaccharides. Only pectins resemble alginate in the sol/gel transition behaviour, but this system can hardly be said to be as well characterised and understood as the alginates. The properties of alginate solutions and gels suggest biomedical and pharmaceutical uses. In this paper, the question of the specifications required by a polymer for applications in some biomedical areas will be discussed. (C) 1997 Elsevier Science B.V.}, added-at = {2011-11-04T13:47:04.000+0100}, address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}, author = {Draget, K. I. and Skjak-Braek, G. and Smidsrod, O.}, biburl = {https://www.bibsonomy.org/bibtex/24dd3c06ae87198bda72f7d07bfa9ec4c/pawelsikorski}, citedref = {DELLAVALLE F, 874014640, EP, APPL ; DRAGET KI, 1988, J PLANT PHYSL, V132, P552 ; DRAGET KI, 1989, APPL MICROBIOL BIOT, V31, P79 ; DRAGET KI, 1994, CARBOHYD POLYM, V25, P31 ; DRAGET KI, 1996, CARBOHYD POLYM, V29, P209 ; ERTESVAG H, 1994, J BACTERIOL, V176, P2846 ; ERTESVAG H, 1995, MOL MICROBIOL, V16, P719 ; GRASDALEN H, 1977, CARBOHYD RES, V56, C11 ; GRASDALEN H, 1979, CARBOHYD RES, V68, P23 ; GRASDALEN H, 1983, CARBOHYD RES, V118, P255 ; HAUG A, 1963, ACTA CHEM SCAND, V17, P1466 ; HAUG A, 1963, ACTA CHEM SCAND, V17, P1653 ; HAUG A, 1967, ACTA CHEM SCAND, V21, P2859 ; KOHN R, 1972, ACTA CHEM SCAND, V26, P2455 ; LARSEN B, 1970, ACTA CHEM SCAND, V24, P726 ; LEO WJ, 1990, BIOTECHNOL PROGR, V6, P51 ; LIM F, 1980, SCIENCE, V210, P908 ; MARTINSEN A, 1992, BIOTECHNOL BIOENG, V39, P186 ; MIKKELSEN A, 1995, BIOPOLYMERS, V36, P1741 ; MOE ST, 1993, MACROMOLECULES, V26, P3589 ; PENMAN A, 1972, CARBOHYD RES, V25, P273 ; SIME WJ, 1990, FOOD GELS, P53 ; SKJAKBRAEK G, 1986, INT J BIOL MACROMOL, V8, P330 ; SKJAKBRAEK G, 1989, CARBOHYD POLYM, V10, P31 ; SKJAKBRAEK G, 1992, 5144016, US ; SKJAKBRAEK G, 1996, CARBOHYDR EUR, V14, P19 ; SMIDSROD O, FOOD COLLOIDS PROTEI, P279 ; SMIDSROD O, 1963, ACTA CHEM SCAND, V17, P1473 ; SMIDSROD O, 1963, ACTA CHEM SCAND, V17, P2628 ; SMIDSROD O, 1967, CARBOHYD RES, V5, P482 ; SMIDSROD O, 1969, MACROMOLECULES, V2, P42 ; SMIDSROD O, 1972, ACTA CHEM SCAND, V26, P79 ; SMIDSROD O, 1974, FARADAY DISCUSS, V57, P263 ; SMIDSROD O, 1990, TRENDS BIOTECHNOL, V8, P71 ; SOONSHIONG P, 1991, TRANSPLANT P 1, V23, P758 ; SOONSHIONG P, 1993, P NATL ACAD SCI USA, V90, P5843 ; SOONSHIONG P, 1994, LANCET, V343, P950 ; SOONSHOING P, 92709364, US ; STOKKE BT, 1993, CARBOHYD POLYM, V21, P39 ; THU B, 1996, BIOMATERIALS, V17, P1031 ; THU B, 1996, BIOMATERIALS, V17, P1069 ; THU B, 1996, IMMOBILIZED CELLS BA, P19}, interhash = {9c6bb83575e41ae80a4ccf3c2089ed6f}, intrahash = {4dd3c06ae87198bda72f7d07bfa9ec4c}, isifile-dt = {Article}, isifile-ga = {XQ942}, isifile-j9 = {INT J BIOL MACROMOL}, isifile-nr = {42}, isifile-pi = {AMSTERDAM}, isifile-rp = {Draget, KI, NORWEGIAN UNIV SCI & TECHNOL,DEPT BIOTECHNOL,NORWEGIAN ; BIOPOLYMER LAB,NBOIPOL,N-7034 TRONDHEIM,NORWAY.}, isifile-sc = {Biochemistry & Molecular Biology}, isifile-tc = {73}, issn = {0141-8130}, journal = {Int. J. Biol. Macromol.}, keywords = {; ;; [ISI:] acid; alginates; azotobacter-vinelandii; chemical-composition; gels; islets polysaccharides residues; sequence; uronate}, language = {English}, month = AUG, number = {1-2}, owner = {phpts}, pages = {47 -- 55}, publisher = {ELSEVIER SCIENCE BV}, size = {9 p.}, sourceid = {ISI:A1997XQ94200008}, timestamp = {2011-11-04T13:47:09.000+0100}, title = {Alginate based new materials}, volume = 21, year = 1997 }