%0 Journal Article %1 Singhi2003 %A Singhi, Pratibha %A Jagirdar, Sujeet %A Khandelwal, Narendra %A Malhi, Prahbhjot %D 2003 %J J Child Neurol %K Adolescent; Age of Onset; Anticonvulsants; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Mental Retardation; Retrospective Seizures; Tomography, X-Ray Computed %N 3 %P 174--179 %T Epilepsy in children with cerebral palsy. %V 18 %X To study the spectrum of epilepsy in children with cerebral palsy, 105 consecutive children with cerebral palsy and active epilepsy, between 1 and 14 years of age, were studied prospectively. A detailed history and examination, electroencephalography (EEG), and computed tomography (CT) were done in all cases. The social quotient was assessed using the Vineland Social Maturity Scale. A retrospective cohort of 452 cases of cerebral palsy was studied to find the prevalence of epilepsy in cerebral palsy. A control group of 60 age-matched children with cerebral palsy but no epilepsy was also studied for comparison of the social quotient. Of the 105 children, 65 were male, 40 of 105 (38\%) had a history of birth asphyxia. The mean age of onset of seizures was 18.9 months; 64 (60.95\%) had seizure onset before 1 year of age. Children with myoclonic seizures (P < .05) and infantile spasms (P < .01) had seizure onset significantly early in life. Generalized seizures were the most common, followed by partial seizures, infantile spasms, and other myoclonic seizures. Seizures were controlled in 45 (58.1\%) children, and polytherapy was required in 40 children. EEG and CT abnormalities were seen in 70.5\% and 61\% of the children. Seizure control was achieved in 74\% of the patients with a normal to borderline social quotient compared with 48.7\% with a social quotient less than 70. Social quotient values had a positive correlation with age of onset of seizures (P < .01) and with better control of seizures (P < .01). Of the cohort of 452 children, 160 (35.4\%) had epilepsy. The maximum incidence (66\%) was seen in children with spastic hemiplegia, followed by quadriplegia (42.6\%) and diplegia (15.8\%). Epilepsy in cerebral palsy is seen in about one third of cases; it is often severe and difficult to control particularly in children with mental retardation.

@article{Singhi2003, abstract = {To study the spectrum of epilepsy in children with cerebral palsy, 105 consecutive children with cerebral palsy and active epilepsy, between 1 and 14 years of age, were studied prospectively. A detailed history and examination, electroencephalography (EEG), and computed tomography (CT) were done in all cases. The social quotient was assessed using the Vineland Social Maturity Scale. A retrospective cohort of 452 cases of cerebral palsy was studied to find the prevalence of epilepsy in cerebral palsy. A control group of 60 age-matched children with cerebral palsy but no epilepsy was also studied for comparison of the social quotient. Of the 105 children, 65 were male, 40 of 105 (38\%) had a history of birth asphyxia. The mean age of onset of seizures was 18.9 months; 64 (60.95\%) had seizure onset before 1 year of age. Children with myoclonic seizures (P < .05) and infantile spasms (P < .01) had seizure onset significantly early in life. Generalized seizures were the most common, followed by partial seizures, infantile spasms, and other myoclonic seizures. Seizures were controlled in 45 (58.1\%) children, and polytherapy was required in 40 children. EEG and CT abnormalities were seen in 70.5\% and 61\% of the children. Seizure control was achieved in 74\% of the patients with a normal to borderline social quotient compared with 48.7\% with a social quotient less than 70. Social quotient values had a positive correlation with age of onset of seizures (P < .01) and with better control of seizures (P < .01). Of the cohort of 452 children, 160 (35.4\%) had epilepsy. The maximum incidence (66\%) was seen in children with spastic hemiplegia, followed by quadriplegia (42.6\%) and diplegia (15.8\%). Epilepsy in cerebral palsy is seen in about one third of cases; it is often severe and difficult to control particularly in children with mental retardation.}, added-at = {2014-07-19T21:21:55.000+0200}, author = {Singhi, Pratibha and Jagirdar, Sujeet and Khandelwal, Narendra and Malhi, Prahbhjot}, biburl = {https://www.bibsonomy.org/bibtex/21b04080230c6f507fa0d44cb77d57b45/ar0berts}, groups = {public}, interhash = {a0249fdb43e4b3af39c78898fc1590bf}, intrahash = {1b04080230c6f507fa0d44cb77d57b45}, journal = {J Child Neurol}, keywords = {Adolescent; Age of Onset; Anticonvulsants; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Mental Retardation; Retrospective Seizures; Tomography, X-Ray Computed}, month = Mar, number = 3, pages = {174--179}, pmid = {12731642}, timestamp = {2014-07-19T21:21:55.000+0200}, title = {Epilepsy in children with cerebral palsy.}, username = {ar0berts}, volume = 18, year = 2003 }