%0 Journal Article %1 rahman2020critical %A Rahman, Mohammad Tariqur %A Idid, Syed Zahir %D 2020 %J Biological Trace Element Research %K covid-19 zinc %R 10.1007/s12011-020-02194-9 %T Can Zn Be a Critical Element in COVID-19 Treatment? %U https://doi.org/10.1007/s12011-020-02194-9 %X The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19.

@article{rahman2020critical, abstract = {The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19.}, added-at = {2020-09-10T08:46:11.000+0200}, author = {Rahman, Mohammad Tariqur and Idid, Syed Zahir}, biburl = {https://www.bibsonomy.org/bibtex/2449ed55739c16ef785144bd0007324fe/fordham1}, day = 26, description = {Can Zn Be a Critical Element in COVID-19 Treatment? | SpringerLink}, doi = {10.1007/s12011-020-02194-9}, interhash = {a4956fa30868b5bc11d2c03ae5dc92e5}, intrahash = {449ed55739c16ef785144bd0007324fe}, issn = {1559-0720}, journal = {Biological Trace Element Research}, keywords = {covid-19 zinc}, month = may, timestamp = {2020-09-10T08:46:11.000+0200}, title = {Can Zn Be a Critical Element in COVID-19 Treatment?}, url = {https://doi.org/10.1007/s12011-020-02194-9}, year = 2020 }