Abstract
In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl)propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg2+) in HEPES buffer under physiological conditions. Possible interference with other analytes was examined. PMR displays a highly selective decrease of its fluorescence at 460 nm when it reacts with Hg2+. Interestingly, the probe can also be used as a fluorescent turn-on sensor for biologically relevant thiols such as glutathione and cysteine. PMR can be used to determine mercury in living cells.
- biothiols,
- chemodosimeter,
- coumarin
- derivatives,
- design,
- dqcauchile
- fluorescent
- fluorescent,
- hg(ii)
- hg2+
- hg2+-selectivity,
- ions,
- molecules,
- probe,
- recognition,
- rhodamine-based
- sensor
Users
Please
log in to take part in the discussion (add own reviews or comments).