Article,

Potentiometric electrode measurement of serum antibodies based on the complement fixation test

, and .
Analytica Chimica Acta, 109 (1): 25--31 (August 1979)
DOI: 10.1016/S0003-2670(01)84222-7

Abstract

Trimethylphenylaminoniuin-selective electrodes are used in the measurement of serum antibodies to bovine serum albumin, with serum complement and sensitized, marker-loaded sheep red blood cell ghosts as mediators. The result is a sensitive and reproducible assay system for the antibody in the presence of its antigen. In addition, the method described is shown to be valuable for basic studies of immune complex--complement interactions.

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