Article,

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout

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N Engl J Med, 378 (13): 1200--1210 (Mar 12, 2018)
DOI: 10.1056/nejmoa1710895

Abstract

Cardiovascular Safety of Febuxostat Patients with gout and cardiovascular disease were assigned to receive febuxostat or allopurinol. At 32 months, there was no significant between-group difference in a composite cardiovascular end point, but all-cause and cardiovascular mortality were higher with febuxostat.

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