Synthesis and receptor affinity of polysubstituted adenosines
S. Vittori, E. Camaioni, S. Costanzi, R. Volpini, K. Klotz, и G. Cristalli. Nucleosides Nucleotides, 18 (4-5):
739-40(апреля 1999)Vittori, S Camaioni, E Costanzi, S Volpini, R Klotz, K N Cristalli,
G United states Nucleosides & nucleotides Nucleosides Nucleotides.
1999 Apr-May;18(4-5):739-40..
In a search for potent and selective adenosine agonists it has been
found that 2-hexynyladenosine-5'-N-ethyluronamide (HENECA) displays
high affinity at rat A2A receptor combined with a good A2A vs A1
selectivity. The finding that HENECA shows good affinity also for
A3 receptors prompted us to investigate the effect of various substituents
in different positions of this molecule.
Vittori, S Camaioni, E Costanzi, S Volpini, R Klotz, K N Cristalli,
G United states Nucleosides & nucleotides Nucleosides Nucleotides.
1999 Apr-May;18(4-5):739-40.
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%0 Journal Article
%1 Vittori1999
%A Vittori, S.
%A Camaioni, E.
%A Costanzi, S.
%A Volpini, R.
%A Klotz, K. N.
%A Cristalli, G.
%D 1999
%J Nucleosides Nucleotides
%K & Adenosine/*analogs Animals Binding CHO Cricetinae Humans P1/*metabolism Protein Proteins/metabolism Purinergic Rats Recombinant derivatives/chemical synthesis/metabolism Receptor Cell
%N 4-5
%P 739-40
%T Synthesis and receptor affinity of polysubstituted adenosines
%U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10432676
%V 18
%X In a search for potent and selective adenosine agonists it has been
found that 2-hexynyladenosine-5'-N-ethyluronamide (HENECA) displays
high affinity at rat A2A receptor combined with a good A2A vs A1
selectivity. The finding that HENECA shows good affinity also for
A3 receptors prompted us to investigate the effect of various substituents
in different positions of this molecule.
@article{Vittori1999,
abstract = {In a search for potent and selective adenosine agonists it has been
found that 2-hexynyladenosine-5'-N-ethyluronamide (HENECA) displays
high affinity at rat A2A receptor combined with a good A2A vs A1
selectivity. The finding that HENECA shows good affinity also for
A3 receptors prompted us to investigate the effect of various substituents
in different positions of this molecule.},
added-at = {2010-12-14T18:12:02.000+0100},
author = {Vittori, S. and Camaioni, E. and Costanzi, S. and Volpini, R. and Klotz, K. N. and Cristalli, G.},
biburl = {https://www.bibsonomy.org/bibtex/2c9b4bae61a9665c7821066efcf764464/pharmawuerz},
endnotereftype = {Journal Article},
interhash = {bb5cc2aace0770e2e4a38a119514fec0},
intrahash = {c9b4bae61a9665c7821066efcf764464},
issn = {0732-8311 (Print) 0732-8311 (Linking)},
journal = {Nucleosides Nucleotides},
keywords = {& Adenosine/*analogs Animals Binding CHO Cricetinae Humans P1/*metabolism Protein Proteins/metabolism Purinergic Rats Recombinant derivatives/chemical synthesis/metabolism Receptor Cell},
month = {Apr-May},
note = {Vittori, S Camaioni, E Costanzi, S Volpini, R Klotz, K N Cristalli,
G United states Nucleosides \& nucleotides Nucleosides Nucleotides.
1999 Apr-May;18(4-5):739-40.},
number = {4-5},
pages = {739-40},
shorttitle = {Synthesis and receptor affinity of polysubstituted adenosines},
timestamp = {2010-12-14T18:20:41.000+0100},
title = {Synthesis and receptor affinity of polysubstituted adenosines},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10432676},
volume = 18,
year = 1999
}