%0 Journal Article %1 salmon2020repeated %A Salmon, Pablo %A Jacobs, Arne %A Ahren, Dag %A Biard, Clotilde %A Dingemanse, Niels %A Dominoni, Davide %A Helm, Barbara %A Lundberg, Max %A Senar, Juan Carlos %A Sprau, Philipp %A Visser, Marcel E %A Isaksson, Caroline %D 2020 %I Cold Spring Harbor Laboratory %J bioRxiv %K blue_tits genome_wide_scan local_adaptation urban_adaptation %R 10.1101/2020.05.05.078568 %T Repeated genomic signatures of adaptation to urbanisation in a songbird across Europe %U https://www.biorxiv.org/content/early/2020/05/07/2020.05.05.078568 %X Urbanisation is currently increasing worldwide, and there is now ample evidence of phenotypic changes in wild organisms in response to this novel environment, but the extent to which this adaptation is due to genetic changes is poorly understood. Current evidence for evolution is based on localised studies, and thus lacking replicability. Here, we genotyped great tits (Parus major) from nine cities across Europe, each paired with a rural site, and provide evidence of repeated polygenic responses to urban habitats. In addition, we show that selective sweeps occurred in response to urbanisation within the same genes across multiple cities. These genetic responses were mostly associated with genes related to neural function and development, demonstrating that genetic adaptation to urbanisation occurred around the same pathways in wildlife populations across a large geographical scale.Competing Interest StatementThe authors have declared no competing interest.

@article{salmon2020repeated, abstract = {Urbanisation is currently increasing worldwide, and there is now ample evidence of phenotypic changes in wild organisms in response to this novel environment, but the extent to which this adaptation is due to genetic changes is poorly understood. Current evidence for evolution is based on localised studies, and thus lacking replicability. Here, we genotyped great tits (Parus major) from nine cities across Europe, each paired with a rural site, and provide evidence of repeated polygenic responses to urban habitats. In addition, we show that selective sweeps occurred in response to urbanisation within the same genes across multiple cities. These genetic responses were mostly associated with genes related to neural function and development, demonstrating that genetic adaptation to urbanisation occurred around the same pathways in wildlife populations across a large geographical scale.Competing Interest StatementThe authors have declared no competing interest.}, added-at = {2020-05-08T01:54:23.000+0200}, author = {Salmon, Pablo and Jacobs, Arne and Ahren, Dag and Biard, Clotilde and Dingemanse, Niels and Dominoni, Davide and Helm, Barbara and Lundberg, Max and Senar, Juan Carlos and Sprau, Philipp and Visser, Marcel E and Isaksson, Caroline}, biburl = {https://www.bibsonomy.org/bibtex/25497a3591633e65ad117734ef3ec696a/peter.ralph}, doi = {10.1101/2020.05.05.078568}, elocation-id = {2020.05.05.078568}, eprint = {https://www.biorxiv.org/content/early/2020/05/07/2020.05.05.078568.full.pdf}, interhash = {c6a38ce2c7a5439e0837aaa544bb2972}, intrahash = {5497a3591633e65ad117734ef3ec696a}, journal = {bioRxiv}, keywords = {blue_tits genome_wide_scan local_adaptation urban_adaptation}, publisher = {Cold Spring Harbor Laboratory}, timestamp = {2020-05-08T01:54:23.000+0200}, title = {Repeated genomic signatures of adaptation to urbanisation in a songbird across {Europe}}, url = {https://www.biorxiv.org/content/early/2020/05/07/2020.05.05.078568}, year = 2020 }