Article,
Features of the Aggregate State of Blood in Patients with Ischemic Heart Disease Combined with Type 2 Diabetes Mellitus
CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (4): 526-531 (August 2023)
Abstract
The article presents an overview of a study on the aggregation state of blood in patients with coronary heart disease combined with type 2 diabetes mellitus. The presence of diabetes is associated with an increased risk of all forms of coronary heart disease, including angina pectoris, non-painful myocardial ischemia, myocardial infarction, as well as sudden cardiac death. As an ischemic heart disease, diabetes mellitus is also characterized by various disorders of coagulation, fibrinolysis, anticoagulant system, platelet function. These factors make a significant contribution to the appearance and progression of atherosclerosis and cardiovascular diseases in patients with type 2 diabetes mellitus. Coronary heart disease in diabetic patients, in comparison with patients without it, develops at an earlier age and is characterized by a more severe lesion of the coronary arteries with involvement of the distal bed. Diabetic disorders have been shown to trigger the natural mechanisms of platelet activation and reduce the levels of endogenous inhibitors of platelet activity.
