%0 Journal Article %1 Barr2000 %A de Barr, Meirelles Kalil Pessoa %A Rodrigues, C. J. %A de Barros, T. E. %A Bevilacqua, R. G. %D 2000 %J J Pediatr Orthop %K Alleles; Apolipoprotein E4; Apolipoproteins E; Cerebral Palsy; Female; Humans; Male; Risk Factors %N 6 %P 786--789 %T Presence of apolipoprotein E epsilon4 allele in cerebral palsy. %V 20 %X The apolipoprotein E gene, which is located on chromosome 19, has three alleles (epsilon2, epsilon3, and epsilon4). Several recent publications associate the presence of the apolipoprotein E epsilon4 allele with the occurrence of neurologic diseases, and consider it a risk factor for the development of central nervous system affections. A group of 40 patients with cerebral palsy was studied and compared to a control group of 40 subjects, and higher occurrence of the allele epsilon4 in the group of subjects with cerebral palsy was observed. A significantly higher risk of developing cerebral palsy was demonstrated among those subjects with the apolipoprotein E epsilon4 allele.

@article{Barr2000, abstract = {The apolipoprotein E gene, which is located on chromosome 19, has three alleles (epsilon2, epsilon3, and epsilon4). Several recent publications associate the presence of the apolipoprotein E epsilon4 allele with the occurrence of neurologic diseases, and consider it a risk factor for the development of central nervous system affections. A group of 40 patients with cerebral palsy was studied and compared to a control group of 40 subjects, and higher occurrence of the allele epsilon4 in the group of subjects with cerebral palsy was observed. A significantly higher risk of developing cerebral palsy was demonstrated among those subjects with the apolipoprotein E epsilon4 allele.}, added-at = {2014-07-19T17:54:09.000+0200}, author = {de Barr, Meirelles Kalil Pessoa and Rodrigues, C. J. and de Barros, T. E. and Bevilacqua, R. G.}, biburl = {https://www.bibsonomy.org/bibtex/282a36467a20b7a938d551fc6fb55eec8/ar0berts}, groups = {public}, interhash = {ddbe8475f87dffe3177aa69fcb09a2b2}, intrahash = {82a36467a20b7a938d551fc6fb55eec8}, journal = {J Pediatr Orthop}, keywords = {Alleles; Apolipoprotein E4; Apolipoproteins E; Cerebral Palsy; Female; Humans; Male; Risk Factors}, number = 6, pages = {786--789}, pmid = {11097255}, timestamp = {2014-07-19T18:01:57.000+0200}, title = {Presence of apolipoprotein E epsilon4 allele in cerebral palsy.}, username = {ar0berts}, volume = 20, year = 2000 }