Abstract
We report a case of Balo's concentric sclerosis with peculiar MRI
findings. Unlike previously published cases all concentric rings
in our case showed marked enhancement, supporting the view of synchronous
active demyelination in the lesion. Follow-up MRI disclosed a change
of the lesions into a confluent pattern more resembling a typical
large MS plaque. There were no oligoclonal bands or intrathecal
Ig-G synthesis. The hypothesis concerning the pathophysiology of
the lesions' typical and peculiar morphological appearance and its
relationship to multiple sclerosis are briefly discussed.
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