%0 Journal Article %1 Yaqoob1995 %A Yaqoob, M. %A Bashir, A. %A Tareen, K. %A Gustavson, K. H. %A Nazir, R. %A Jalil, F. %A von D?beln, U. %A Ferngren, H. %D 1995 %J Acta Paediatr %K Asphyxia Neonatorum; Cerebral Palsy; Chromosome Aberrations; Disorders; Cohort Studies; Down Syndrome; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Maternal Age; Mental Retardation; Pakistan; Poverty Areas; Social Class %N 3 %P 267--272 %T Severe mental retardation in 2 to 24-month-old children in Lahore, Pakistan: a prospective cohort study. %V 84 %X Severe mental retardation (developmental quotient (DQ) < 50) was investigated in 1303 children from 2 to 24 months of age, born during 1984-87 in four population groups representing different socio-economic levels in and around Lahore, Pakistan. The incidence per 1000 live births was 22 in the periurban slum, 9 in the urban slum, 7 in the village and 4 in the upper middle class group. The aetiology was prenatal in 79\%, perinatal in 14\% and untraceable in 7\% of cases. Down's syndrome was the most common cause of severe mental retardation (36\%). Impairments were studied at 2 years of age. Impairment of language was present in all, while locomotor dysfunction was seen in 89\% of cases. Epilepsy and cerebral palsy were each present in 22\% of cases. Mortality among these severely mentally retarded children was 36\%.

@article{Yaqoob1995, abstract = {Severe mental retardation (developmental quotient (DQ) < 50) was investigated in 1303 children from 2 to 24 months of age, born during 1984-87 in four population groups representing different socio-economic levels in and around Lahore, Pakistan. The incidence per 1000 live births was 22 in the periurban slum, 9 in the urban slum, 7 in the village and 4 in the upper middle class group. The aetiology was prenatal in 79\%, perinatal in 14\% and untraceable in 7\% of cases. Down's syndrome was the most common cause of severe mental retardation (36\%). Impairments were studied at 2 years of age. Impairment of language was present in all, while locomotor dysfunction was seen in 89\% of cases. Epilepsy and cerebral palsy were each present in 22\% of cases. Mortality among these severely mentally retarded children was 36\%.}, added-at = {2014-07-20T09:29:56.000+0200}, author = {Yaqoob, M. and Bashir, A. and Tareen, K. and Gustavson, K. H. and Nazir, R. and Jalil, F. and von D?beln, U. and Ferngren, H.}, biburl = {https://www.bibsonomy.org/bibtex/26da01740a281e77e47d082142a95feb7/ar0berts}, groups = {public}, interhash = {fe3492cf23c4c6dd973dc670c1b5cdf1}, intrahash = {6da01740a281e77e47d082142a95feb7}, journal = {Acta Paediatr}, keywords = {Asphyxia Neonatorum; Cerebral Palsy; Chromosome Aberrations; Disorders; Cohort Studies; Down Syndrome; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Maternal Age; Mental Retardation; Pakistan; Poverty Areas; Social Class}, month = Mar, number = 3, pages = {267--272}, pmid = {7780247}, timestamp = {2014-07-20T09:29:56.000+0200}, title = {Severe mental retardation in 2 to 24-month-old children in Lahore, Pakistan: a prospective cohort study.}, username = {ar0berts}, volume = 84, year = 1995 }