Article,

Neonatal ultrasonographic cerebral findings: association with risk factor for cerebral palsy

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Z Geburtshilfe Neonatol, 206 (4): 142--150 (2002)
DOI: 10.1055/s-2002-33668

Abstract

BACKGROUND: Is it possible to identify patients with cerebral palsy (CP) with postnatal ultrasound scan? Which risk factors are associated with an increased risk of CP?. PATIENTS AND METHODS: The data of 37 children with CP, who were sonographically investigated during the first 24 hours of life were analyzed retrospectively. The data of 21 preterm infants with gestational age </= 32 wk were compared with the data of 59 without CP. RESULTS: A tetraparesis was found in 15/21 of preterm babies </= 32 wk, a hemiparesis in 4/8 of premature infants >/= 33 wk and in 5/8 of the mature babies. The mature babies had prenatal brain atrophy or hypoxic-ischaemic cerebral lesions. Cytomegaly and encephalitis were detected in two babies. Immature babies >/= 33 wk showed prenatal porencephaly or encephalomalacia after asphyxia. Premature babies </= 32 wk had cystic periventricular leucomalacia (n=12) or cerebral haemorrhage (n=3); 3 babies had meningitis. Only two prematures </= 32 wk with mild CP had inconspicuous ultrasound scans. Factors associated with cerebral palsy were: cystic periventricular leucomalacia (OR 24,89; 95 \% CI: 5,85 - 105,87), cerebral atrophy (OR 4,84; 95 \% CI: 1,61 - 14,51), fetal hypoxia (CTG) - (OR 4,78; 95 \% CI: 1,31 - 17,45), abruptio placentae (OR 4,32; 95 \% CI: 1,16 - 16,13), anemia after birth (OR 18,13; 95 \% CI: 1,97 - 166,43), abnormal neurological behavior at term (OR 14,00; 95 \% CI: 3,29 - 59,55). CONCLUSION: Cerebral ultrasound scan after birth is a useful method detect for cerebral lesions in patients with CP-risks.

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