A laser fiber was delivered via a catheter inserted through a perineal template and guided to the target with MRI. The tissue temperature was monitored during laser ablation by MRI thermometry. Accumulated thermal damage was calculated in real time. Immediate post-treatment contrast-enhanced MRI confirmed devascularization of the target. No adverse events were noted. MRI-guided focal laser therapy of low-risk PCa is feasible and may offer a good balance between cancer control and side effects.
T. Paul, Y. Hasegawa, and H. Iba. Proceedings of the 2006 IEEE Congress on Evolutionary
Computation, page 2521--2528. Vancouver, BC, Canada, IEEE Computational Intelligence Society, IEEE Press, (16-21 July 2006)
T. Paul, and H. Iba. Genetic Programming Theory and Practice IV, volume 5 of Genetic and Evolutionary Computation, chapter 10, Springer, Ann Arbor, (11-13 May 2006)
A. Bankhead III, and R. Heckendorn. Genetic Programming and Evolvable Machines, 8 (4):
381--393(December 2007)special issue on medical applications of Genetic and
Evolutionary Computation.
A. Almal, A. Mitra, R. Datar, P. Lenehan, D. Fry, R. Cote, and W. Worzel. GECCO 2006: Proceedings of the 8th annual conference
on Genetic and evolutionary computation, 1, page 239--246. Seattle, Washington, USA, ACM Press, (8-12 July 2006)
T. Paul, Y. Hasegawa, and H. Iba. Proceedings of the 2006 IEEE Congress on Evolutionary Computation, page 2521--2528. Vancouver, BC, Canada, IEEE Computational Intelligence Society, IEEE Press, (16-21 July 2006)