Pinax is an open-source platform built on the Django Web Framework. By integrating numerous reusable Django apps to take care of the things that many sites have in common, it lets you focus on what makes your site different.
Myghty is a Python based templating framework originally based on HTML::Mason, the enterprise-level framework used by Amazon.com, del.icio.us and Salon.com,
Sajax is an open source tool to make programming websites using the Ajax framework — also known as XMLHTTPRequest or remote scripting — as easy as possible. Sajax makes it easy to call PHP, Perl or Python functions from your webpages via JavaScript without performing a browser refresh. The toolkit does 99% of the work for you so you have no excuse to not use it.
Allegra is an innovative library for web peer applications development. It provides a framework for asynchronous network peer programming, a simple stack of Internet standards implementations, and two new network applications: a disruptive metabase peer a
Clever Harold is an ambitious web development framework written in the Python programming language. It has many features for rapid, reusable, and reliable web application construction.