Alexandre Vanautgaerden's research shows that Erasmus never ceased to adapt, depending on each type of text, the layouts of his books to best control their reception. A reversal of the traditional countdown of the exegesis of Erasmus's works, which lends at times a blind faith to his correspondence, this present work focuses on the study of manuscripts and printed books. Erasmus would not settle for just writing his texts, but preoccupied himself, with a growing scrupulousness, with the manner in which they would be read. In addition to this new biography of an Erasmus who we discover riveted to the material existence of his books, the reader will find a great number of unedited documents (printers' letters, preliminary works), in Latin or in translation, as well as a list of the humanist's first editions. This volume offers a new look on the status of authors and readers at the beginning of the 16th century. It will interest historians of books as much as of humanism.