Abstract
Detection of gamma-glutamyl transpeptidase (GGT; ggt ) activity is one of the useful methods for a specific identification of Neisseria meningitidis. However, we previously happened to isolate a ggt -deficient N. meningitidis strain (NIID113) from a healthy carrier. In this study, in order to re-examine the reliability of the marker, we again investigated the GGT activity of 245 N. meningitidis human isolates and identified two other GGT-defective N. meningitidis isolates besides NIID113. The isolation frequency (1.2\%) of ggt mutants among human isolates strongly confirmed the 98.8\% reliability of GGT activity as the identification marker for N. meningitidis.
- adult,
- aged,
- bacterial,
- carrier
- data,
- genes,
- humans,
- infections,
- japan,
- male,
- meningitidis,
- meningococcal
- middle
- molecular
- mutation,
- neisseria
- of
- reproducibility
- results,
- sequence
- species
- specificity,
- state,
- thailand
- {gamma-glutamyltransferase,}
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