%0 Journal Article %1 beharee2020effect %A Beharee, Nitish %A Shi, Zujun %A Cui, Yaping %A Cheng, Xianzhong %A Wang, Jinhua %D 2020 %E Wu, Jiang %J Advances in Biochemistry and Biotechnology (ISSN: 2574-7258) %K %N 1 %P 7 %R 10.29011/2574-7258.001096 %T The Effect of Maternal Age at First Pregnancy on the Risk of Gynaecological Cancers – A Literature Review and Retrospective Analysis %U https://gavinpublishers.com/articles/review-article/Advances-in-Biochemistry-and-Biotechnology/the-effect-of-maternal-age-at-first-pregnancy-on-the-risk-of-gynaecological-cancers-a-literature-review-and-retrospective-analysis %V 5 %X Background: What impact does the age of first pregnancy has on the incidence of gynecological cancers? The major objective of our study was to test the hypothesis that the earlier the age of first pregnancy, the lesser the risk of gynecological cancers among women in Jiangsu Province, Nanjing, China. Method: We collected cases of gynecologic cancer patients diagnosed between 2015 and 2018 to evaluate the impact that the age of first pregnancy might have on the incidence of gynecological cancers. Participants’ data were collected from the Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research registry. Gynecologic cancer cases were subdivided into uterine, ovarian and cervical cancers. Patients’ obstetric history and age of first pregnancy were recorded. As a control group, women who have not been pregnant but suffered from gynecological cancer within the same period were selected. No animals/human tissue were used in this study, and thus no ethical committee was set up for approval. Result: Based on the statistical findings of this study, it can be concluded that the age of first pregnancy has an impact on the risk of gynecological cancers. Conclusion: This analysis provides an evaluation of the age of first pregnancy and its relative effect on the incidence of gynecologic cancer. If the age of first pregnancy has an impact on the incidence of gynecological cancer, this can be used accordingly to reduce the risk. It is to be noted that age of first pregnancy, is not to be confused with age of first delivery. The first pregnancy might have been concluded by a delivery or by an abortion (procured and spontaneous). Like any other study, this study had its own shortcomings as well. One of the major short coming of this study was that the number of pregnancies couldn’t be used as an indicative parameter because of the ‘One Child Policy’ prevailing in China

@article{beharee2020effect, abstract = {Background: What impact does the age of first pregnancy has on the incidence of gynecological cancers? The major objective of our study was to test the hypothesis that the earlier the age of first pregnancy, the lesser the risk of gynecological cancers among women in Jiangsu Province, Nanjing, China. Method: We collected cases of gynecologic cancer patients diagnosed between 2015 and 2018 to evaluate the impact that the age of first pregnancy might have on the incidence of gynecological cancers. Participants’ data were collected from the Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research registry. Gynecologic cancer cases were subdivided into uterine, ovarian and cervical cancers. Patients’ obstetric history and age of first pregnancy were recorded. As a control group, women who have not been pregnant but suffered from gynecological cancer within the same period were selected. No animals/human tissue were used in this study, and thus no ethical committee was set up for approval. Result: Based on the statistical findings of this study, it can be concluded that the age of first pregnancy has an impact on the risk of gynecological cancers. Conclusion: This analysis provides an evaluation of the age of first pregnancy and its relative effect on the incidence of gynecologic cancer. If the age of first pregnancy has an impact on the incidence of gynecological cancer, this can be used accordingly to reduce the risk. It is to be noted that age of first pregnancy, is not to be confused with age of first delivery. The first pregnancy might have been concluded by a delivery or by an abortion (procured and spontaneous). Like any other study, this study had its own shortcomings as well. One of the major short coming of this study was that the number of pregnancies couldn’t be used as an indicative parameter because of the ‘One Child Policy’ prevailing in China}, added-at = {2020-01-30T06:12:43.000+0100}, author = {Beharee, Nitish and Shi, Zujun and Cui, Yaping and Cheng, Xianzhong and Wang, Jinhua}, biburl = {https://www.bibsonomy.org/bibtex/2c7a7f3987ae175a30f1707e244140e9c/alyssacarter}, doi = {10.29011/2574-7258.001096}, editor = {Wu, Jiang}, interhash = {8017844eca61d2979635a56d6e263149}, intrahash = {c7a7f3987ae175a30f1707e244140e9c}, issn = {2574-7258}, journal = {Advances in Biochemistry and Biotechnology (ISSN: 2574-7258)}, keywords = {}, language = {English}, month = {January}, number = 1, pages = 7, timestamp = {2020-01-30T06:12:43.000+0100}, title = {The Effect of Maternal Age at First Pregnancy on the Risk of Gynaecological Cancers – A Literature Review and Retrospective Analysis}, url = {https://gavinpublishers.com/articles/review-article/Advances-in-Biochemistry-and-Biotechnology/the-effect-of-maternal-age-at-first-pregnancy-on-the-risk-of-gynaecological-cancers-a-literature-review-and-retrospective-analysis}, volume = 5, year = 2020 }