%0 Conference Paper %1 rowland:2004:ogpakditd %A Rowland, Jem %B Proceedings of the 2004 IEEE Congress on Evolutionary Computation %C Portland, Oregon %D 2004 %I IEEE Press %K Bioinformatics Biology Computation Computational Evolutionary algorithms, and genetic in programming, %P 158--165 %T On Genetic Programming and Knowledge Discovery in Transcriptome Data %X This paper concerns the use of Genetic Programming (GP) for supervised classification of transcriptome (gene expression) data. In such applications GP can produce accurate predictive models that generalize well and use only very few gene expression values. It is often suggested that the selected genes are therefore of biological significance in discriminating the classes. The paper presents a preliminary study of successful parsimonious GP models to investigate the extent to which the selected variables contribute to the classification. The work is based on a readily available and well studied dataset that represents gene expression values for two groups of patients with different forms of Leukaemia. %@ 0-7803-8515-2

@inproceedings{rowland:2004:ogpakditd, abstract = {This paper concerns the use of Genetic Programming (GP) for supervised classification of transcriptome (gene expression) data. In such applications GP can produce accurate predictive models that generalize well and use only very few gene expression values. It is often suggested that the selected genes are therefore of biological significance in discriminating the classes. The paper presents a preliminary study of successful parsimonious GP models to investigate the extent to which the selected variables contribute to the classification. The work is based on a readily available and well studied dataset that represents gene expression values for two groups of patients with different forms of Leukaemia.}, added-at = {2008-06-19T17:46:40.000+0200}, address = {Portland, Oregon}, author = {Rowland, Jem}, biburl = {https://www.bibsonomy.org/bibtex/27d52d9454ee28d82eb1fe876b70a545d/brazovayeye}, booktitle = {Proceedings of the 2004 IEEE Congress on Evolutionary Computation}, interhash = {a0f50f975699ffb82d5cb1f5444bc6b3}, intrahash = {7d52d9454ee28d82eb1fe876b70a545d}, isbn = {0-7803-8515-2}, keywords = {Bioinformatics Biology Computation Computational Evolutionary algorithms, and genetic in programming,}, month = {20-23 June}, notes = {CEC 2004 - A joint meeting of the IEEE, the EPS, and the IEE.}, pages = {158--165}, publisher = {IEEE Press}, timestamp = {2008-06-19T17:50:46.000+0200}, title = {On Genetic Programming and Knowledge Discovery in Transcriptome Data}, year = 2004 }