In a two-dimensional stepping-stone model of finite size, if a pair of
alleles happen to segregate in the whole population, marked local differ- entiation of gene frequencies can occur only if migration between colonies
is sufficiently rare so that Nm < 1, where N is the effective size of each
colony and m is the rate at which each colony exchanges individuals with
four surrounding colonies each generation. On the other hand, if Nm ^ 4, the whole population behaves as if it were panmictic and the allelic fre- quencies become uniform over the entire distribution range unless muta- tion is unusually high. Tendency toward local differentiation is much
weaker in two-dimensional than in one-dimensional habitats.
%0 Journal Article
%1 kimura1971pattern
%A Kimura, M
%A Maruyama, T
%D 1971
%J Genet Res
%K spatial_coalescent spatial_structure stepping_stone_models
%N 2
%P 125-131
%T Pattern of neutral polymorphism in a geographically structured population
%U https://www.ncbi.nlm.nih.gov/pubmed/5159222
%V 18
%X In a two-dimensional stepping-stone model of finite size, if a pair of
alleles happen to segregate in the whole population, marked local differ- entiation of gene frequencies can occur only if migration between colonies
is sufficiently rare so that Nm < 1, where N is the effective size of each
colony and m is the rate at which each colony exchanges individuals with
four surrounding colonies each generation. On the other hand, if Nm ^ 4, the whole population behaves as if it were panmictic and the allelic fre- quencies become uniform over the entire distribution range unless muta- tion is unusually high. Tendency toward local differentiation is much
weaker in two-dimensional than in one-dimensional habitats.
@article{kimura1971pattern,
abstract = {In a two-dimensional stepping-stone model of finite size, if a pair of
alleles happen to segregate in the whole population, marked local differ- entiation of gene frequencies can occur only if migration between colonies
is sufficiently rare so that Nm < 1, where N is the effective size of each
colony and m is the rate at which each colony exchanges individuals with
four surrounding colonies each generation. On the other hand, if Nm ^ 4, the whole population behaves as if it were panmictic and the allelic fre- quencies become uniform over the entire distribution range unless muta- tion is unusually high. Tendency toward local differentiation is much
weaker in two-dimensional than in one-dimensional habitats.},
added-at = {2017-10-09T20:06:41.000+0200},
author = {Kimura, M and Maruyama, T},
biburl = {https://www.bibsonomy.org/bibtex/2ba86843757240c25b1bc272e7c257c24/peter.ralph},
interhash = {30e14d3584a0c99ecff5555d32e5478c},
intrahash = {ba86843757240c25b1bc272e7c257c24},
journal = {Genet Res},
keywords = {spatial_coalescent spatial_structure stepping_stone_models},
month = oct,
number = 2,
pages = {125-131},
pmid = {5159222},
timestamp = {2017-10-09T20:06:41.000+0200},
title = {Pattern of neutral polymorphism in a geographically structured population},
url = {https://www.ncbi.nlm.nih.gov/pubmed/5159222},
volume = 18,
year = 1971
}