%0 Journal Article %1 Kelley2012 %A Kelley, Maureen %A Edwards, Kelly %A Starks, Helene %A Fullerton, Stephanie M %A James, Rosalina %A Goering, Sara %A Holland, Suzanne %A Disis, Mary L %A Burke, Wylie %D 2012 %J Clinical and translational science %K Health Humans Judgment TranslationalMedicalResearch %N 6 %P 445-51 %R 10.1111/j.1752-8062.2012.00441.x %T Values in translation: how asking the right questions can move translational science toward greater health impact. %U http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3561695&tool=pmcentrez&rendertype=abstract %V 5 %X The speed and effectiveness of current approaches to research translation are widely viewed as disappointing given small gains in real population health outcomes despite huge investments in basic and translational science. We identify critical value questions-ethical, social, economic, and cultural-that arise at moments throughout the research pathway. By making these questions visible, and promoting discussion of them with diverse stakeholders, we can facilitate handoffs along the translational pathway and increase uptake of effective interventions. Who is involved with those discussions will determine which research projects, populations, and methods get prioritized. We argue that some upfront investment in community and interdisciplinary engagement, shaped by familiar questions in ethics, social justice, and cultural knowledge, can save time and resources in the long run because interventions and strategies will be aimed in the right direction, that is, toward health improvements for all. %@ 1752-8062

@article{Kelley2012, abstract = {The speed and effectiveness of current approaches to research translation are widely viewed as disappointing given small gains in real population health outcomes despite huge investments in basic and translational science. We identify critical value questions-ethical, social, economic, and cultural-that arise at moments throughout the research pathway. By making these questions visible, and promoting discussion of them with diverse stakeholders, we can facilitate handoffs along the translational pathway and increase uptake of effective interventions. Who is involved with those discussions will determine which research projects, populations, and methods get prioritized. We argue that some upfront investment in community and interdisciplinary engagement, shaped by familiar questions in ethics, social justice, and cultural knowledge, can save time and resources in the long run because interventions and strategies will be aimed in the right direction, that is, toward health improvements for all.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Kelley, Maureen and Edwards, Kelly and Starks, Helene and Fullerton, Stephanie M and James, Rosalina and Goering, Sara and Holland, Suzanne and Disis, Mary L and Burke, Wylie}, biburl = {https://www.bibsonomy.org/bibtex/2c440f4c846116bb064eec2baad0a0e42/jepcastel}, city = {Treuman Katz Center for Pediatric Bioethics, Seattle Children's Hospital, Washington, USA. mckelley@u.washington.edu}, doi = {10.1111/j.1752-8062.2012.00441.x}, interhash = {63f040c9d2b7ef1f5b0490b1b8e5f52c}, intrahash = {c440f4c846116bb064eec2baad0a0e42}, isbn = {1752-8062}, issn = {1752-8062}, journal = {Clinical and translational science}, keywords = {Health Humans Judgment TranslationalMedicalResearch}, month = {12}, note = {7398<m:linebreak></m:linebreak>CI: (c) 2012; GR: P50 HG3374/HG/NHGRI NIH HHS/United States; GR: UL1 RR025014/RR/NCRR NIH HHS/United States; GR: UL1 TR000423/TR/NCATS NIH HHS/United States; JID: 101474067; OID: NLM: PMC3561695; 2012/08/07 [aheadofprint]; ppublish;<m:linebreak></m:linebreak>Recerca clínica}, number = 6, pages = {445-51}, pmid = {23253665}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {Values in translation: how asking the right questions can move translational science toward greater health impact.}, url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3561695&tool=pmcentrez&rendertype=abstract}, volume = 5, year = 2012 }