Abstract Biological self-assembly is very complex and results in highly
functional materials. In effect, it takes a bottom-up approach using
biomolecular building blocks of precisely defined shape, size, hydrophobicity,
and spatial distribution of functionality. Inspired by, and drawing
lessons from self-assembly processes in nature, scientists are learning
how to control the balance of many small forces to increase the complexity
and functionality of self-assembled nanomaterials. The coiled-coil
motif, a multipurpose building block commonly found in nature, has
great potential in synthetic biology. In this review we examine the
roles that the coiled-coil peptide motif plays in self-assembly in
nature, and then summarize the advances that this has inspired in
the creation of functional units, assemblies, and systems.
%0 Journal Article
%1 Robsona Marsden2010
%A Robsonâ Marsden, Hana
%A Kros, Alexander
%D 2010
%I WILEY-VCH Verlag
%J Angewandte Chemie International Edition
%K biology chemistry, coiled coils, molecular peptides, recognition, supramolecular synthetic
%N 17
%P 2988--3005
%R 10.1002/anie.200904943
%T Self-Assembly of Coiled Coils in Synthetic Biology: Inspiration and
Progress
%U http://dx.doi.org/10.1002/anie.200904943
%V 49
%X Abstract Biological self-assembly is very complex and results in highly
functional materials. In effect, it takes a bottom-up approach using
biomolecular building blocks of precisely defined shape, size, hydrophobicity,
and spatial distribution of functionality. Inspired by, and drawing
lessons from self-assembly processes in nature, scientists are learning
how to control the balance of many small forces to increase the complexity
and functionality of self-assembled nanomaterials. The coiled-coil
motif, a multipurpose building block commonly found in nature, has
great potential in synthetic biology. In this review we examine the
roles that the coiled-coil peptide motif plays in self-assembly in
nature, and then summarize the advances that this has inspired in
the creation of functional units, assemblies, and systems.
@article{Robsona Marsden2010,
abstract = {Abstract Biological self-assembly is very complex and results in highly
functional materials. In effect, it takes a bottom-up approach using
biomolecular building blocks of precisely defined shape, size, hydrophobicity,
and spatial distribution of functionality. Inspired by, and drawing
lessons from self-assembly processes in nature, scientists are learning
how to control the balance of many small forces to increase the complexity
and functionality of self-assembled nanomaterials. The coiled-coil
motif, a multipurpose building block commonly found in nature, has
great potential in synthetic biology. In this review we examine the
roles that the coiled-coil peptide motif plays in self-assembly in
nature, and then summarize the advances that this has inspired in
the creation of functional units, assemblies, and systems.},
added-at = {2011-11-04T13:47:04.000+0100},
author = {Robsonâ Marsden, Hana and Kros, Alexander},
biburl = {https://www.bibsonomy.org/bibtex/2e0f67febfb19744931222342cb0f1e25/pawelsikorski},
doi = {10.1002/anie.200904943},
interhash = {d5479f8cc095c2c8730587d8cc12d695},
intrahash = {e0f67febfb19744931222342cb0f1e25},
issn = {1521-3773},
journal = {Angewandte Chemie International Edition},
keywords = {biology chemistry, coiled coils, molecular peptides, recognition, supramolecular synthetic},
number = 17,
owner = {phpts},
pages = {2988--3005},
publisher = {WILEY-VCH Verlag},
timestamp = {2011-11-04T13:47:23.000+0100},
title = {Self-Assembly of Coiled Coils in Synthetic Biology: Inspiration and
Progress},
url = {http://dx.doi.org/10.1002/anie.200904943},
volume = 49,
year = 2010
}