Article,

A novel Cardiovascular Risk Marker Among Young Adults’ Patient with Coronary Artery Disease in Basra Province

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5): 843-853 (September 2023)

Abstract

Background; Despite the absence of classic CVD risk factors, patients still have CVD events, prompting the quest for novel markers of CVD risk. Given inflammation's central involvement in atherosclerosis, inflammatory biomarkers have emerged as promising indicators. Particularly useful in predicting cardiovascular risk across a wide range of patient populations are measures of C-reactive protein (CRP), Leptin, and ceruloplasmin. Higher levels of hs Crp and Leptin were found in patients with CVD compared to controls, although ceruloplasmin showed no statistically significant differences. Methodology: The study comprised 90 patients diagnosed by coronary angiography. Participants in this study (53 males and 37 females) with CAD, their ages ranged from 25-45 years, the patient and control who attended Al-Sadr Teaching Hospital and Naft Al-Basra Specialized Heart Hospital, Basra, Iraq between from December 2022 to the end of September 2023 in Basrah, Southern Iraq. Leptin was measured using an (ELISA). hsCrp.ceruloplasmin was also measured using an Cobas e411. Results; Leptin, hsCrp levels were significantly higher in patients compared to age-matched healthy controls, ceruloplasmin levels were non significantly between patients compared to age-matched healthy controls, according to the current study.

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