Article,

Dinoprostone in the Induction of Labor in Women with Late and Term Preeclampsia

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5): 107-114 (September 2023)

Abstract

Preeclampsia in the structure of causes of maternal mortality occupy a leading position. It is known that only delivery cures preeclampsia. But until now, the success of induction depending on the method, the choice of medication for induction in preterm gestation, obstetric and perinatal outcomes depending on the method of labor induction in women with preeclampsia remain controversial. A comparative analysis of obstetric and perinatal outcomes of women with «de novo» preeclampsia whose used induction of labor with dinoprostone and women whose labor began after amniotomy was carried out. It has been shown that the use of dinoprostone does not increase the incidence of complications in childbirth and the postpartum period and does not worsen perinatal outcomes compared with mechanical induction by amniotomy. It has been established that the use of dinoprostone simulates the physiological process of delivery, when the maturation of the cervix precedes labor, and the duration of labor after induction with dinoprostone does not statistically significantly differ in women with full-term and late preeclampsia. The results of this study prove the clinical efficacy and safety of using dinoprostone for preinduction and induction of labor in women with late and term preeclampsia.

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