%0 Journal Article %1 Neufeld2005 %A Neufeld, Michael D %A Frigon, Chantal %A Graham, Alan S %A Mueller, Beth A %D 2005 %J J Perinatol %K Case-Control Studies; Cerebral Palsy; Chorioamnionitis; Cystitis; Female; Fever; Humans; Infant, Newborn; Premature; Premature, Diseases; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Urinary Tract Infections %N 2 %P 108--113 %R 10.1038/sj.jp.7211219 %T Maternal infection and risk of cerebral palsy in term and preterm infants. %U http://dx.doi.org/10.1038/sj.jp.7211219 %V 25 %X OBJECTIVE: We tested the hypothesis that term and preterm infants exposed to maternal infection at the time of delivery are at increased risk of developing cerebral palsy (CP). STUDY DESIGN: A population-based case-control study was conducted using Washington State birth certificate data linked to hospital discharge data. Cases (688) were children <or=6 years old, singleton births, hospitalized during 1987 to 1999 with an ICD-9 diagnosis code for CP. Controls were 3,068 singleton birth infants randomly selected from birth records for the same years without CP-related hospitalizations. Infection information was available only for the birth hospitalization. RESULTS: Infants of women who had any infection during their hospitalization for delivery were at increased risk of CP (odds ratio (OR) 3.1, 95\% confidence interval (CI) 2.3 to 4.2). This was observed for term deliveries (OR 1.8, 95\% CI 1.1 to 2.8) and preterm deliveries (OR 2.3, 95\% CI 1.3 to 4.2). CONCLUSIONS: Our results suggest that maternal infection is a risk factor for CP in both term and preterm infants.

@article{Neufeld2005, abstract = {OBJECTIVE: We tested the hypothesis that term and preterm infants exposed to maternal infection at the time of delivery are at increased risk of developing cerebral palsy (CP). STUDY DESIGN: A population-based case-control study was conducted using Washington State birth certificate data linked to hospital discharge data. Cases (688) were children <or=6 years old, singleton births, hospitalized during 1987 to 1999 with an ICD-9 diagnosis code for CP. Controls were 3,068 singleton birth infants randomly selected from birth records for the same years without CP-related hospitalizations. Infection information was available only for the birth hospitalization. RESULTS: Infants of women who had any infection during their hospitalization for delivery were at increased risk of CP (odds ratio (OR) 3.1, 95\% confidence interval (CI) 2.3 to 4.2). This was observed for term deliveries (OR 1.8, 95\% CI 1.1 to 2.8) and preterm deliveries (OR 2.3, 95\% CI 1.3 to 4.2). CONCLUSIONS: Our results suggest that maternal infection is a risk factor for CP in both term and preterm infants.}, added-at = {2014-07-19T20:54:20.000+0200}, author = {Neufeld, Michael D and Frigon, Chantal and Graham, Alan S and Mueller, Beth A}, biburl = {https://www.bibsonomy.org/bibtex/2061db4797199bd24408f174d97a5d7af/ar0berts}, doi = {10.1038/sj.jp.7211219}, groups = {public}, interhash = {d851990c6c4ac2aa9af49879910583eb}, intrahash = {061db4797199bd24408f174d97a5d7af}, journal = {J Perinatol}, keywords = {Case-Control Studies; Cerebral Palsy; Chorioamnionitis; Cystitis; Female; Fever; Humans; Infant, Newborn; Premature; Premature, Diseases; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Urinary Tract Infections}, month = Feb, number = 2, pages = {108--113}, pii = {7211219}, pmid = {15538398}, timestamp = {2014-07-19T20:54:20.000+0200}, title = {Maternal infection and risk of cerebral palsy in term and preterm infants.}, url = {http://dx.doi.org/10.1038/sj.jp.7211219}, username = {ar0berts}, volume = 25, year = 2005 }