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Benefits, challenges and obstacles of adaptive clinical trial designs.

, and . Orphanet journal of rare diseases, (January 2011)6593<m:linebreak></m:linebreak>GR: 2P30 AI064518/AI/NIAID NIH HHS/United States; JID: 101266602; OID: NLM: PMC3248853; 2011/08/22 received; 2011/11/30 accepted; 2011/11/30 aheadofprint; epublish;<m:linebreak></m:linebreak>Tipus d&#039;estudis; Dissenys adaptatius.
DOI: 10.1186/1750-1172-6-79

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Benefits, challenges and obstacles of adaptive clinical trial designs., and . Orphanet journal of rare diseases, (January 2011)6593<m:linebreak></m:linebreak>GR: 2P30 AI064518/AI/NIAID NIH HHS/United States; JID: 101266602; OID: NLM: PMC3248853; 2011/08/22 received; 2011/11/30 accepted; 2011/11/30 aheadofprint; epublish;<m:linebreak></m:linebreak>Tipus d&#039;estudis; Dissenys adaptatius.Clinical predictors of major infections after cardiac surgery., , , , , and . Circulation, 112 (9 Suppl): I358--I365 (August 2005)Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial., , , , , , , , , and 8 other author(s). JAMA, 309 (13): 1368--1378 (April 2013)