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The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site

, , , , , , and . J Biol Chem, 278 (10): 8052-7 (March 2003)Eichmann, Tanja Lorenz, Kristina Hoffmann, Michaela Brockmann, Jorg Krasel, Cornelius Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2003 Mar 7;278(10):8052-7. Epub 2002 Dec 16..

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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2, , and . Nature, 426 (6966): 574-9 (December 2003)Lorenz, Kristina Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't England Nature Nature. 2003 Dec 4;426(6966):574-9..Paradoxical block of parathormone secretion is mediated by increased activity of G alpha subunits, , , and . J Biol Chem, 276 (9): 6763-9 (March 2001)Quitterer, U Hoffmann, M Freichel, M Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Mar 2;276(9):6763-9. Epub 2000 Dec 1..Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange, and . Proc Natl Acad Sci U S A, 96 (19): 10626-31 (September 1999)Quitterer, U Lohse, M J United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10626-31..Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding, , , , , , and . J Biol Chem, 280 (20): 20042-50 (May 2005)Humrich, Jan Bermel, Christina Bunemann, Moritz Harmark, Linda Frost, Robert Quitterer, Ursula Lohse, Martin J In Vitro United States The Journal of biological chemistry J Biol Chem. 2005 May 20;280(20):20042-50. Epub 2005 Mar 2..Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein-coupled receptor kinases, , , , and . Proc Natl Acad Sci U S A, 96 (10): 5476-81 (May 1999)Dicker, F Quitterer, U Winstel, R Honold, K Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1999 May 11;96(10):5476-81..The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site, , , , , , and . J Biol Chem, 278 (10): 8052-7 (March 2003)Eichmann, Tanja Lorenz, Kristina Hoffmann, Michaela Brockmann, Jorg Krasel, Cornelius Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2003 Mar 7;278(10):8052-7. Epub 2002 Dec 16..Binding of Gbetagamma subunits to cRaf1 downregulates G-protein-coupled receptor signalling, , , , , and . Curr Biol, 9 (17): 971-4 (September 1999)Slupsky, J R Quitterer, U Weber, C K Gierschik, P Lohse, M J Rapp, U R Research Support, Non-U.S. Gov't England Current biology : CB Curr Biol. 1999 Sep 9;9(17):971-4..Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2, , , , , and . J Biol Chem, 275 (38): 29724-30 (September 2000)Ruiz-Gomez, A Humrich, J Murga, C Quitterer, U Lohse, M J Mayor, F Jr Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 2000 Sep 22;275(38):29724-30..Effector coupling of stably transfected human A3 adenosine receptors in CHO cells, , and . Biochem Pharmacol, 64 (1): 61-5 (July 2002)Englert, Martin Quitterer, Ursula Klotz, Karl Norbert England Biochemical pharmacology Biochem Pharmacol. 2002 Jul 1;64(1):61-5..SUMO-1 controls the protein stability and the biological function of phosducin, , , and . J Biol Chem, 281 (13): 8357-64 (March 2006)Klenk, Christoph Humrich, Jan Quitterer, Ursula Lohse, Martin J Comparative Study Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2006 Mar 31;281(13):8357-64. Epub 2006 Jan 18..