Statins have pleiotropic effects: anti-inflammatory, immunomodulatory, antithrombotic, and vascular activity, & may improve left ventricular myocardial function & left ventricular diastolic function by increasing vascular elasticity.
S. Hammerschmidt, M. Bell, N. Buchler, H. Wahn, H. Remkes, M. Lohse, and S. Neubauer. Biochim Biophys Acta, 1502 (3):
471-80(November 2000)Hammerschmidt, S Bell, M Buchler, N Wahn, H Remkes, H Lohse, M J
Neubauer, S In Vitro Netherlands Biochimica et biophysica acta Biochim
Biophys Acta. 2000 Nov 15;1502(3):471-80..
S. Engelhardt, L. Hein, V. Dyachenkow, E. Kranias, G. Isenberg, and M. Lohse. Circulation, 109 (9):
1154-60(March 2004)Engelhardt, Stefan Hein, Lutz Dyachenkow, Vitaly Kranias, Evangelia
G Isenberg, Gerrit Lohse, Martin J HL26057/HL/NHLBI NIH HHS/United
States HL52318/HL/NHLBI NIH HHS/United States HL64018/HL/NHLBI NIH
HHS/United States Research Support, Non-U.S. Gov't Research Support,
U.S. Gov't, P.H.S. United States Circulation Circulation. 2004 Mar
9;109(9):1154-60. Epub 2004 Feb 16..
S. Engelhardt, M. Bohm, E. Erdmann, and M. Lohse. J Am Coll Cardiol, 27 (1):
146-54(January 1996)Engelhardt, S Bohm, M Erdmann, E Lohse, M J Research Support, Non-U.S.
Gov't United states Journal of the American College of Cardiology
J Am Coll Cardiol. 1996 Jan;27(1):146-54..
R. Jahns, V. Boivin, C. Siegmund, G. Inselmann, M. Lohse, and F. Boege. Circulation, 99 (5):
649-54(February 1999)Jahns, R Boivin, V Siegmund, C Inselmann, G Lohse, M J Boege, F Research
Support, Non-U.S. Gov't United states Circulation Circulation. 1999
Feb 9;99(5):649-54..
S. Neubauer, M. Frank, K. Hu, H. Remkes, A. Laser, M. Horn, G. Ertl, and M. Lohse. J Mol Cell Cardiol, 30 (4):
803-10(April 1998)Neubauer, S Frank, M Hu, K Remkes, H Laser, A Horn, M Ertl, G Lohse,
M J Research Support, Non-U.S. Gov't England Journal of molecular
and cellular cardiology J Mol Cell Cardiol. 1998 Apr;30(4):803-10..