Clinical case conference- Present illness: A 27-year-old female patient with chronic post-traumatic stress disorder (PTSD) and recurrent major depressive sisorder (MDD) is referred for consultation regarding possible repetitive transcranial magnetic stimulation (rTMS) treatment for her medication-resistant depression. She has no other medical diagnoses and had no history of substance abuse.. To read the full article, log in using your NHS OpenAthens details.
Vortioxetine and serotonin-norepinephrine reuptake inhibitors (SNRIs) may have similar effectiveness in improving outcomes for adults with depression. However, evidence from randomized controlled trials is of very low quality, and we are uncertain about research findings.
To compare pupil responses in depressed patients with a seasonal pattern, depressed patients without a seasonal pattern and healthy controls as a function of daylight hours on the testing day. . To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Psychology of Religion and Spirituality Vol. 10, Iss. 1, (Feb 2018): 79-87.
We compared the effectiveness of religiously integrated cognitive–behavioral therapy (RCBT) versus conventional CBT (CCBT) on decreasing suicidal thoughts in persons with major depressive disorder (MDD) and chronic medical illness (CMI).. To read the full article, log in using your NHS OpenAthens details.
Journal of Abnormal Psychology Vol. 127, Iss. 1, (Jan 2018): 1-11.
The hopelessness theory of depression is a prominent account of depression that posits that individuals with a negative inferential style are more likely to become hopeless when they experience negative life events (NLEs) and that hopelessness is a proximal cause of depression. There is strong evidence supporting the role of a negative inferential style in the pathogenesis of major depression; however, substantially less is known about the proposed role played by hopelessness.. To read the full article, log in using your NHS OpenAthens details.
Depression is an important contributor to the global burden of disease. Besides several known individual-level factors that contribute to depression, there is a growing recognition that neighbourhood environment can also profoundly affect mental health. This study assessed associations between three neighbourhood constructs—socioeconomic deprivation, residential instability and income inequality—and depression among adult twin pairs. The twin design is used to examine the association between neighbourhood constructs and depression, controlling for selection factors (ie, genetic and shared environmental factors) that have confounded purported associations.
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The risk of relapse in major depressive disorder (MDD) is associated with high worldwide disease burden. Cognitive behavioral therapy (CBT) and its modifications might be effective in relapse prevention. The aim of this review was to evaluate the efficacy of these treatments for reducing relapse of MDD.
Depression after hip fracture in older adults is associated with worse physical performance; however, depressive symptoms are dynamic, fluctuating during the recovery period. The study aim was to determine how the persistence of depressive symptoms over time cumulatively affects the recovery of physical performance.. To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Editorial. In this issue of JAMA Psychiatry, Daly and colleagues4 present intriguing findings from the first clinical trial of intranasal esketamine hydrochloride (the more potent S-enantiomer of ketamine) adjunctive to oral antidepressants in TRD, reporting on its efficacy, safety, and dose response.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
People with major depressive disorder frequently exhibit increasing persistence of major depressive episodes. However, evidence for neuroprogression (ie, increasing brain pathology with longer duration of illness) is scarce. Microglial activation, which is an important component of neuroinflammation, is implicated in neuroprogression. We examined the relationship of translocator protein (TSPO) total distribution volume (VT), a marker of microglial activation, with duration of untreated major depressive disorder, and with total illness duration and antidepressant exposure.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Editorial. In this issue of JAMA Psychiatry, Gordon et al1 report results from a 12-month randomized clinical trial of estrogen plus progestin hormone therapy (HT) vs placebo for the prevention of depressive symptoms in 172 euthymic perimenopausal and early postmenopausal women.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
How do effects of genetics and rearing each contribute to the transmission of risk for major depression from parents to children?. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
The transition to adulthood is a major developmental milestone; a time of self-discovery and increased independence. For young adults (YA) with intellectual disabilities (ID), however, this period is especially challenging. The increased incidence of mental health disorders in this population, such as depression and anxiety, make this transition even more difficult, increasing caregiver burden at a time when the young adult would traditionally be gaining independence. It is not clear, however, why YA with ID are more susceptible and what factors may predict mental health symptoms.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Treatment-resistant major depression (TRMD) in veterans is a major clinical challenge given the high risk for suicidality in these patients. Repetitive transcranial magnetic stimulation (rTMS) offers the potential for a novel treatment modality for these veterans.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Anxiety and depression are common in inflammatory bowel disease (IBD) and have been linked to clinical recurrence. Previous randomized controlled trials (RCT's) have found no evidence that psychological interventions enhance outcomes for people with IBD but have recruited patients without distress. This study investigates the clinical benefits of a nonrandomized uncontrolled study of clinic based cognitive behaviour therapy (CBT) for people with IBD who had moderate–severe levels of anxiety or low mood and compares the results with a previous RCT of CBT in this population. . To read the full article, log in using your MPFT NHS OpenAthens details.
Depressive disorders arise from a combination of genetic and environmental risk factors. Epigenetic disruption provides a plausible mechanism through which gene-environment interactions lead to depression. Large-scale, epigenome-wide studies on depression are missing, hampering the identification of potentially modifiable biomarkers.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Psychological Medicine; Cambridge Vol. 48, Iss. 14, (Oct 2018): 2285-2298.
Comorbid depression in the medically ill is clinically important. Admission to a general hospital offers an opportunity to identify and initiate treatment for depression. However, we first need to know how common depression is in general hospital inpatients. We aimed to address this question by systematically reviewing the relevant literature. . To read the full article, log in using your MPFT NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 48, Iss. 14, (Oct 2018): 2329-2336.
Access to transition-related medical interventions (TRMIs) for transgender veterans has been the subject of substantial public interest and debate. To better inform these important conversations, the current study investigated whether undergoing hormone or surgical transition intervention(s) relates to the frequency of recent suicidal ideation (SI) and symptoms of depression in transgender veterans.. To read the full article, log in using your MPFT NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 48, Iss. 14, (Oct 2018): 2439-2448.
Complicated and persistent grief reactions afflict approximately 10% of bereaved individuals and are associated with severe disruptions of functioning. These maladaptive patterns were defined in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) as persistent complex bereavement disorder (PCBD), but its criteria remain debated. The condition has been studied using network analysis, showing potential for an improved understanding of PCBD. However, previous studies were limited to self-report and primarily originated from a single archival dataset.. To read the full article, log in using your MPFT NHS OpenAthens details.
A. B, E. CR, F. T, G. FA, K. T, B. G, K. N, and M. S. Cochrane Database of Systematic Reviews, (2009)Art. No.: CD 007954. DOI: 10. 1002 / 14651858. CD 007954.