Anti-Inflammatory Effects of Pioglitazone and/or Simvastatin in High Cardiovascular Risk Patients With Elevated High Sensitivity C-Reactive Protein The PIOSTAT Study
While the cause of statin-associated myopathy is controversial, a central role for coenzyme Q10 (CoQ10 or ubiquinone) is slowly gaining acceptance. Statins have been shown to create an acquired CoQ10 deficiency.
Eating walnuts can reverse the impairment of endothelial function associated with eating a fatty meal. But olive oil did not have the same beneficial effect. "When we eat a fatty meal, inflammatory molecules are increased that prevent the endothelium fro
ntake of Fish Oil, Oleic Acid, Folic Acid, and Vitamins B-6 and E for 1 Year Decreases Plasma C-Reactive Protein and Reduces Coronary Heart Disease Risk Factors in Male Patients in a Cardiac Rehabilitation Program1
Statins exert their pleiotropic effects, in part, by improving endothelial function via up-regulation of endothelial nitric oxide synthase enzyme activity.
Experimental as well as clinical data do not support the hypothesis that atorvastatin or any other statin affects the antithrombotic potency of clopidogrel.
Coronary collateral circulation is associated with preserved myocardial contractility; preexisting collaterals may be more important than neoangiogenesis for angina & MI patients.
Raymond Gibbons, MD (Mayo Clinic, Pres/American Heart Association), said COURAGE trial findings suggest that "hundreds of thousands of Americans with stable angina who received coronary stents did not need them."
Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction