The AMPA receptor is involved in a process known as long-term potentiation, or LTP – believed to underlie the encoding of many types of memory. In addition to its importance to memory formation, the AMPA receptor plays a central role in “excitatory co
AMPA modulators might ameliorate memory deficits that occur in dementia, such as Alzheimer's disease (AD). However, AMPA receptor mediated excitotoxicity may occur with excessive AMPA receptor activation which occurs in seizures or ischaemia and positive