This summary of "Python-based Template Packages" comes from discussions on the webware-discuss list. Here is an index of various packages sorted such that Pythonic, Webware-onic and stable packages float to the top of the list. There is a detailed key at the bottom for the column semantics.
plasTeX is a LaTeX document processing framework written entirely in Python. It currently comes bundled with an XHTML renderer (including multiple themes), as well as a way to simply dump the document to a generic form of XML. Other renderers can be added as well and are planned for future releases.