Article,

Perspectives on the basic reproductive ratio

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Journal of The Royal Society Interface, 2 (4): 281-293 (2005)
DOI: 10.1098/rsif.2005.0042

Abstract

The basic reproductive ratio, $R_0$, is defined as the expected number of secondary infections arising from a single individual during his or her entire infectious period, in a population of susceptibles. This concept is fundamental to the study of epidemiology and within-host pathogen dynamics. Most importantly, often serves as a threshold parameter that predicts whether an infection will spread. Related parameters which share this threshold behaviour, however, may or may not give the true value of . In this paper we give a brief overview of common methods of formulating and surrogate threshold parameters from deterministic, non-structured models. We also review common means of estimating from epidemiological data. Finally, we survey the recent use of in assessing emerging diseases, such as severe acute respiratory syndrome and avian influenza, a number of recent livestock diseases, and vector-borne diseases malaria, dengue and West Nile virus.

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