%0 Journal Article %1 Dehal:2002:Science:12481130 %A Dehal, P %A Satou, Y %A Campbell, R K %A Chapman, J %A Degnan, B %A Tomaso, A De %A Davidson, B %A Gregorio, A Di %A Gelpke, M %A Goodstein, D M %A Harafuji, N %A Hastings, K E %A Ho, I %A Hotta, K %A Huang, W %A Kawashima, T %A Lemaire, P %A Martinez, D %A Meinertzhagen, I A %A Necula, S %A Nonaka, M %A Putnam, N %A Rash, S %A Saiga, H %A Satake, M %A Terry, A %A Yamada, L %A Wang, H G %A Awazu, S %A Azumi, K %A Boore, J %A Branno, M %A Chin-Bow, S %A DeSantis, R %A Doyle, S %A Francino, P %A Keys, D N %A Haga, S %A Hayashi, H %A Hino, K %A Imai, K S %A Inaba, K %A Kano, S %A Kobayashi, K %A Kobayashi, M %A Lee, B I %A Makabe, K W %A Manohar, C %A Matassi, G %A Medina, M %A Mochizuki, Y %A Mount, S %A Morishita, T %A Miura, S %A Nakayama, A %A Nishizaka, S %A Nomoto, H %A Ohta, F %A Oishi, K %A Rigoutsos, I %A Sano, M %A Sasaki, A %A Sasakura, Y %A Shoguchi, E %A i, T Shin %A Spagnuolo, A %A Stainier, D %A Suzuki, M M %A Tassy, O %A Takatori, N %A Tokuoka, M %A Yagi, K %A Yoshizaki, F %A Wada, S %A Zhang, C %A Hyatt, P D %A Larimer, F %A Detter, C %A Doggett, N %A Glavina, T %A Hawkins, T %A Richardson, P %A Lucas, S %A Kohara, Y %A Levine, M %A Satoh, N %A Rokhsar, D S %D 2002 %J Science %K imported %N 5601 %P 2157-2167 %R 10.1126/science.1080049 %T The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins %U http://www.ncbi.nlm.nih.gov/pubmed/12481130?dopt=AbstractPlus&holding=f1000,f1000m,isrctn %V 298 %X The first chordates appear in the fossil record at the time of the Cambrian explosion, nearly 550 million years ago. The modern ascidian tadpole represents a plausible approximation to these ancestral chordates. To illuminate the origins of chordate and vertebrates, we generated a draft of the protein-coding portion of the genome of the most studied ascidian, Ciona intestinalis. The Ciona genome contains approximately 16,000 protein-coding genes, similar to the number in other invertebrates, but only half that found in vertebrates. Vertebrate gene families are typically found in simplified form in Ciona, suggesting that ascidians contain the basic ancestral complement of genes involved in cell signaling and development. The ascidian genome has also acquired a number of lineage-specific innovations, including a group of genes engaged in cellulose metabolism that are related to those in bacteria and fungi.

@article{Dehal:2002:Science:12481130, abstract = {The first chordates appear in the fossil record at the time of the Cambrian explosion, nearly 550 million years ago. The modern ascidian tadpole represents a plausible approximation to these ancestral chordates. To illuminate the origins of chordate and vertebrates, we generated a draft of the protein-coding portion of the genome of the most studied ascidian, Ciona intestinalis. The Ciona genome contains approximately 16,000 protein-coding genes, similar to the number in other invertebrates, but only half that found in vertebrates. Vertebrate gene families are typically found in simplified form in Ciona, suggesting that ascidians contain the basic ancestral complement of genes involved in cell signaling and development. The ascidian genome has also acquired a number of lineage-specific innovations, including a group of genes engaged in cellulose metabolism that are related to those in bacteria and fungi.}, added-at = {2009-11-19T22:16:03.000+0100}, author = {Dehal, P and Satou, Y and Campbell, R K and Chapman, J and Degnan, B and Tomaso, A De and Davidson, B and Gregorio, A Di and Gelpke, M and Goodstein, D M and Harafuji, N and Hastings, K E and Ho, I and Hotta, K and Huang, W and Kawashima, T and Lemaire, P and Martinez, D and Meinertzhagen, I A and Necula, S and Nonaka, M and Putnam, N and Rash, S and Saiga, H and Satake, M and Terry, A and Yamada, L and Wang, H G and Awazu, S and Azumi, K and Boore, J and Branno, M and Chin-Bow, S and DeSantis, R and Doyle, S and Francino, P and Keys, D N and Haga, S and Hayashi, H and Hino, K and Imai, K S and Inaba, K and Kano, S and Kobayashi, K and Kobayashi, M and Lee, B I and Makabe, K W and Manohar, C and Matassi, G and Medina, M and Mochizuki, Y and Mount, S and Morishita, T and Miura, S and Nakayama, A and Nishizaka, S and Nomoto, H and Ohta, F and Oishi, K and Rigoutsos, I and Sano, M and Sasaki, A and Sasakura, Y and Shoguchi, E and i, T Shin and Spagnuolo, A and Stainier, D and Suzuki, M M and Tassy, O and Takatori, N and Tokuoka, M and Yagi, K and Yoshizaki, F and Wada, S and Zhang, C and Hyatt, P D and Larimer, F and Detter, C and Doggett, N and Glavina, T and Hawkins, T and Richardson, P and Lucas, S and Kohara, Y and Levine, M and Satoh, N and Rokhsar, D S}, biburl = {https://www.bibsonomy.org/bibtex/213b6798bce99e9d063f160539f9faa27/cchen63}, description = {The draft genome of Ciona intestinalis: insights i... [Science. 2002] - PubMed result}, doi = {10.1126/science.1080049}, interhash = {f48bf15e4e887b92ea32ff5fd7b6ab99}, intrahash = {13b6798bce99e9d063f160539f9faa27}, journal = {Science}, keywords = {imported}, month = Dec, number = 5601, pages = {2157-2167}, pmid = {12481130}, timestamp = {2009-11-19T22:16:03.000+0100}, title = {The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins}, url = {http://www.ncbi.nlm.nih.gov/pubmed/12481130?dopt=AbstractPlus&holding=f1000,f1000m,isrctn}, volume = 298, year = 2002 }