Article,

The Relationship Between White Blood Cell Cunt and Mortality in Patients with Crimean–Congo Hemorrhagic Fever

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5): 871-880 (September 2023)

Abstract

Aim: Crimean–Congo hemorrhagic fever (CCHF) generally affects many organs. In this study a retrospective evaluation of white blood cell and platelet counts, cures, and deaths of CCHF patients was performed to determine the prognostic value of blood count at presentation. . Patients and methods: The records of 100 patients who admitted in Al Hussian Teaching hospital, Nasiriya, south of IRAQ from March to November 2022 were retrospectively analyzed. For each patient an evaluation was made for age, sex, White Blood cell count status. Platelet count ( mild, moderate, sever and critical ) and fate of the patients ( cure or death) . A confirmed diagnosis of CCHF was made on determination by polymerase chain reaction. Results: Of the 100 patients, 45 were female and 55 were male. Leukocytosis was present in only 7% while normal WBC value status in 38% ( 24 male & 14 female), while leukopenia status in 55% ( 27 male & 28 female). Regarding platelet count, most of the patients have severe or moderate thrombocytopenia ( 37% and 34% respectively) , while critical thrombocytopenia seen in 16% most of them are male. The present study showed that mild, moderate, sever and critical count of PLT in young age group 8%, 21%, 27%, and 9% respectively, while the lowest categories of thrombocytopenia in older age group, Most patients with CCHF were cured 77%, while 23% of patients unfortunately died , also the most cure rate was reported among patients with leukopenia (out of 55 patients. 52 were survive) Compared to those with leukocytosis ( out of 7. Only one survive), also among patients who have normal WBC count ( out of 38 patients, 14 were died). In addition to that, the study noted most patients cure from disease with moderate PLT, while most death in those with severe thrombocytopenia. The results also noted a significant difference between status of leukocyte according hospital say of patients. The results noted a non-significant difference between status of platelets and hospital stay Conclusions: This study shows a non-significant difference between status of leukocyte and platelets count according to sex, age group and hospital stay but, The results also noted a significant difference between status of leukocyte and platelets count according to fate of patients. Those who presented with normal or high white blood cell count may stay longer in the hospital and have higher risk of mortality.

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