%0 Journal Article %1 noauthororeditor %A Sharma, Er. Neeshu %A Kumar, Er. Dinesh %A Kaur, Er. Reet Kamal %D 2011 %J International Journal of Computer Science, Engineering and Information Technology (IJCSEIT) %K Analysis HMM Hmm Profile Sequence alignment %N 3 %P 01-10 %R 10.5121/ijcseit.2011.1301 %T HMM’S INTERPOLATION OF PROTIENS FOR PROFILE ANALYSIS %U http://airccse.org/journal/ijcseit/papers/0811ijcseit01.pdf %V 1 %X HMM has found its application in almost every field. Applying Hmm to biological sequences has its own advantages. HMM’s being more systematic and specific, yield a result better than consensus techniques. Profile HMMs use position specific scoring for the matching & substitution of a residue and for the opening or extension of a gap. HMMs apply a statistical method to estimate the true frequency of a residue at a given position in the alignment from its observed frequency while standard profiles use the observed frequency itself to assign the score for that residue. This means that a profile HMM derived from only 10 to 20 aligned sequences can be of equivalent quality to a standard profile created from 40 to 50 aligned sequences.

@article{noauthororeditor, abstract = {HMM has found its application in almost every field. Applying Hmm to biological sequences has its own advantages. HMM’s being more systematic and specific, yield a result better than consensus techniques. Profile HMMs use position specific scoring for the matching & substitution of a residue and for the opening or extension of a gap. HMMs apply a statistical method to estimate the true frequency of a residue at a given position in the alignment from its observed frequency while standard profiles use the observed frequency itself to assign the score for that residue. This means that a profile HMM derived from only 10 to 20 aligned sequences can be of equivalent quality to a standard profile created from 40 to 50 aligned sequences. }, added-at = {2018-10-30T12:29:24.000+0100}, author = {Sharma, Er. Neeshu and Kumar, Er. Dinesh and Kaur, Er. Reet Kamal}, biburl = {https://www.bibsonomy.org/bibtex/290467dd5f519a26acc141cdf55cd8d47/ijcseit}, doi = {10.5121/ijcseit.2011.1301}, interhash = {234c25e59d768c472ad292d076ee6aeb}, intrahash = {90467dd5f519a26acc141cdf55cd8d47}, issn = {2231-3117 [Online] ; 2231-3605 [Print]}, journal = {International Journal of Computer Science, Engineering and Information Technology (IJCSEIT) }, keywords = {Analysis HMM Hmm Profile Sequence alignment}, language = {English}, month = aug, number = 3, pages = {01-10}, timestamp = {2018-10-30T12:29:24.000+0100}, title = {HMM’S INTERPOLATION OF PROTIENS FOR PROFILE ANALYSIS}, url = {http://airccse.org/journal/ijcseit/papers/0811ijcseit01.pdf}, volume = 1, year = 2011 }