All cancers arise as a result of changes that have occurred in the
DNA sequence of the genomes of cancer cells. Over the past quarter
of a century much has been learnt about these mutations and the abnormal
genes that operate in human cancers. We are now, however, moving
into an era in which it will be possible to obtain the complete DNA
sequence of large numbers of cancer genomes. These studies will provide
us with a detailed and comprehensive perspective on how individual
cancers have developed.
%0 Journal Article
%1 Stratton2009cancergenome
%A Stratton, Michael R
%A Campbell, Peter J
%A Futreal, P. Andrew
%D 2009
%J Nature
%K Analysis Genes, Genome, Genomics, Human, Humans; Mutation, Neoplasm, Neoplasms, Sequence genetics; trends;
%N 7239
%P 719--724
%R 10.1038/nature07943
%T The cancer genome.
%U http://dx.doi.org/10.1038/nature07943
%V 458
%X All cancers arise as a result of changes that have occurred in the
DNA sequence of the genomes of cancer cells. Over the past quarter
of a century much has been learnt about these mutations and the abnormal
genes that operate in human cancers. We are now, however, moving
into an era in which it will be possible to obtain the complete DNA
sequence of large numbers of cancer genomes. These studies will provide
us with a detailed and comprehensive perspective on how individual
cancers have developed.
@article{Stratton2009cancergenome,
abstract = {All cancers arise as a result of changes that have occurred in the
DNA sequence of the genomes of cancer cells. Over the past quarter
of a century much has been learnt about these mutations and the abnormal
genes that operate in human cancers. We are now, however, moving
into an era in which it will be possible to obtain the complete DNA
sequence of large numbers of cancer genomes. These studies will provide
us with a detailed and comprehensive perspective on how individual
cancers have developed.},
added-at = {2014-05-13T15:48:44.000+0200},
author = {Stratton, Michael R and Campbell, Peter J and Futreal, P. Andrew},
biburl = {https://www.bibsonomy.org/bibtex/2bedaaf7746d877a196310883f5e477b8/gwotto},
doi = {10.1038/nature07943},
file = {:Stratton2009cancergenome.pdf:PDF},
institution = {Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton,
Cambridge CB10 1SA, UK. mrs@sanger.ac.uk},
interhash = {37e35f9dc1813327f62438bc83b75c80},
intrahash = {bedaaf7746d877a196310883f5e477b8},
journal = {Nature},
keywords = {Analysis Genes, Genome, Genomics, Human, Humans; Mutation, Neoplasm, Neoplasms, Sequence genetics; trends;},
language = {eng},
medline-pst = {ppublish},
month = Apr,
number = 7239,
owner = {gwo},
pages = {719--724},
pii = {nature07943},
pmid = {19360079},
timestamp = {2014-05-13T15:48:44.000+0200},
title = {The cancer genome.},
url = {http://dx.doi.org/10.1038/nature07943},
volume = 458,
year = 2009
}