%0 Journal Article %1 conejo_zinc_2003 %A Conejo, M Carmen %A García, Isabel %A Martínez-Martínez, Luis %A Picabea, Leandro %A Pascual, Alvaro %D 2003 %J Antimicrobial Agents and Chemotherapy %K Bacterial, Carbapenems, Catheterization, Drug Latex, Microbial Porins, Pseudomonas Resistance, Sensitivity Silicon, Tests, Urinary Zinc aeruginosa, %N 7 %P 2313--5 %R 12821486 %T Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa %U http://www.ncbi.nlm.nih.gov/pubmed/12821486 %V 47 %X The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is responsible for this phenomenon. We have found that zinc exerts a negative effect on the expression of OprD, the porin responsible for carbapenem entry into P. aeruginosa.

@article{conejo_zinc_2003, abstract = {The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters {(SLUCs).} This effect was associated with the loss of {OprD.} The zinc that eluted from {SLUCs} is responsible for this phenomenon. We have found that zinc exerts a negative effect on the expression of {OprD,} the porin responsible for carbapenem entry into P. aeruginosa.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Conejo, M Carmen and García, Isabel and {Martínez-Martínez}, Luis and Picabea, Leandro and Pascual, Alvaro}, biburl = {https://www.bibsonomy.org/bibtex/2f8dd72969141a69ba06ac5c732d7a162/jelias}, doi = {12821486}, interhash = {a012e0df5e5d41faa5d20f4706facaf0}, intrahash = {f8dd72969141a69ba06ac5c732d7a162}, issn = {0066-4804}, journal = {Antimicrobial Agents and Chemotherapy}, keywords = {Bacterial, Carbapenems, Catheterization, Drug Latex, Microbial Porins, Pseudomonas Resistance, Sensitivity Silicon, Tests, Urinary Zinc aeruginosa,}, month = jul, note = {{PMID:} 12821486}, number = 7, pages = {2313--5}, timestamp = {2011-03-11T10:06:17.000+0100}, title = {Zinc eluted from siliconized latex urinary catheters decreases {OprD} expression, causing carbapenem resistance in Pseudomonas aeruginosa}, url = {http://www.ncbi.nlm.nih.gov/pubmed/12821486}, volume = 47, year = 2003 }