%0 Journal Article %1 WOS:000498290700033 %A Silva, Alison B %A Pinto, Francisco C L %A Silveira, Edilberto R %A V, Leticia Costa-Lotufo %A Costa, Wendell S %A Ayala, Alejandro Pedro %A Canuto, Kirley M %A Barros, Ayslan B %A Araujo, Ana Jersia %A Filho, Jose Delano B Marinho %A Pessoa, Otilia Deusdenia L %C RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS %D 2019 %I ELSEVIER %J FITOTERAPIA %K 3-Hydroxy-N-methyl-2-oxindole; 4-Hydroxy-pyran-2-one; Antimicrobial Marine X-ray actinomycete; activity} analysis; arenicola; structure {Salinispora %R 10.1016/j.fitote.2019.104357 %T 4-Hydroxy-pyran-2-one and 3-hydroxy-N-methyl-2-oxindole derivatives of Salinispora arenicola from Brazilian marine sediments %V 138 %X Three new 3-hydroxy-N-methyl-2-oxindole (1 and 2) and 4-hydroxy-pyran-2-one (3) derivatives, along with the known 3-hydroxy-N-methyl-2-oxindole (4) and 6-methoxy-N-methylisatin (5) were isolated from a marine Salinispora arenicola strain from sediments of the St. Peter and St. Paul Archipelago, Brazil. The structures of the new compounds were elucidated by a combination of spectroscopic (1D and 2D NMR and HR-ESIMS) data, including single-crystal X-ray diffraction analysis for 2 and 3. Compounds 1 to 5 were assayed for their antimicrobial properties, but only 4 and 5 were active against Enterococcus faecalis with MIC value of 15.6 mu g/mL.

@article{WOS:000498290700033, abstract = {Three new 3-hydroxy-N-methyl-2-oxindole (1 and 2) and 4-hydroxy-pyran-2-one (3) derivatives, along with the known 3-hydroxy-N-methyl-2-oxindole (4) and 6-methoxy-N-methylisatin (5) were isolated from a marine Salinispora arenicola strain from sediments of the St. Peter and St. Paul Archipelago, Brazil. The structures of the new compounds were elucidated by a combination of spectroscopic (1D and 2D NMR and HR-ESIMS) data, including single-crystal X-ray diffraction analysis for 2 and 3. Compounds 1 to 5 were assayed for their antimicrobial properties, but only 4 and 5 were active against Enterococcus faecalis with MIC value of 15.6 mu g/mL.}, added-at = {2022-05-23T20:00:14.000+0200}, address = {RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS}, author = {Silva, Alison B and Pinto, Francisco C L and Silveira, Edilberto R and V, Leticia Costa-Lotufo and Costa, Wendell S and Ayala, Alejandro Pedro and Canuto, Kirley M and Barros, Ayslan B and Araujo, Ana Jersia and Filho, Jose Delano B Marinho and Pessoa, Otilia Deusdenia L}, biburl = {https://www.bibsonomy.org/bibtex/2af5c73f0fd2ed630313618e198c2749f/ppgfis_ufc_br}, doi = {10.1016/j.fitote.2019.104357}, interhash = {3da57efbd52e7dea16ecb2e1ddc6f0b9}, intrahash = {af5c73f0fd2ed630313618e198c2749f}, issn = {0367-326X}, journal = {FITOTERAPIA}, keywords = {3-Hydroxy-N-methyl-2-oxindole; 4-Hydroxy-pyran-2-one; Antimicrobial Marine X-ray actinomycete; activity} analysis; arenicola; structure {Salinispora}, publisher = {ELSEVIER}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {4-Hydroxy-pyran-2-one and 3-hydroxy-N-methyl-2-oxindole derivatives of Salinispora arenicola from Brazilian marine sediments}, tppubtype = {article}, volume = 138, year = 2019 }