%0 Journal Article %1 Paxton2011 %A Paxton, Raheem J. %A Garcia-Prieto, Celia %A Berglund, Maria %A Hernandez, Mike %A Hejek, Richard A. %A Handy, Beverly %A Brown, Jubilee %A Jones, Lovell A. %D 2011 %J Gynecologic Oncology %K %N 0 %P - %R 10.1016/j.ygyno.2011.11.031 %T A randomized parallel-group dietary study for stage ii-iv ovarian cancer survivors %U http://www.sciencedirect.com/science/article/pii/S0090825811009498 %X Abstract BACKGROUND: Few studies have examined the dietary habits of ovarian cancer survivors. Therefore, we conducted a study to assess the feasibility and impact of two dietary interventions for ovarian cancer survivors. METHODS: In this randomized, parallel-group study, 51 women (mean age, 53years) diagnosed with stage II-IV ovarian cancer were recruited and randomly assigned to a low fat, high fiber (LFHF) diet or a modified National Cancer Institute diet supplemented with a soy-based beverage and encapsulated fruit and vegetable juice concentrates (FVJCs). Changes in clinical measures, serum carotenoid and tocopherol levels, dietary intake, anthropometry, and health-related quality of life (HRQOL) were assessed with paired t-tests. RESULTS: The recruitment rate was 25%, and the retention rate was 75% at 6months. At baseline, 28% and 45% of women met guidelines for intake of fiber and of fruits and vegetables, respectively. After 6months, total serum carotenoid levels and α- and β-carotene concentrations were significantly increased in both groups (P<0.01); however, β-carotene concentrations were increased more in the FVJC group. Serum β-cryptoxanthin levels, fiber intake (+5.2g/day), and daily servings of juice (+0.9 servings/day) and vegetables (+1.3 servings/day) were all significantly increased in the LFHF group (all P<0.05). Serum levels of albumin, lutein and zeaxanthin, retinol, and retinyl palmitate were significantly increased in the FVJC group (all P<0.05). No changes in cancer antigen-125, anthropometry, or HRQOL were observed. CONCLUSION: Overall, this study supports the feasibility of designing dietary interventions for stage II-IV ovarian cancer survivors and provides preliminary evidence that a low fat high fiber diet and a diet supplemented with encapsulated FVJC may increase phytonutrients in ovarian cancer survivors.Keywords ovarian cancer, lifestyle, nutrition, diet, cancer survivors, carotenoids, tocopherols, comparative effectiveness, and randomized study.

@article{Paxton2011, abstract = {Abstract BACKGROUND: Few studies have examined the dietary habits of ovarian cancer survivors. Therefore, we conducted a study to assess the feasibility and impact of two dietary interventions for ovarian cancer survivors. METHODS: In this randomized, parallel-group study, 51 women (mean age, 53years) diagnosed with stage II-IV ovarian cancer were recruited and randomly assigned to a low fat, high fiber (LFHF) diet or a modified National Cancer Institute diet supplemented with a soy-based beverage and encapsulated fruit and vegetable juice concentrates (FVJCs). Changes in clinical measures, serum carotenoid and tocopherol levels, dietary intake, anthropometry, and health-related quality of life (HRQOL) were assessed with paired t-tests. RESULTS: The recruitment rate was 25%, and the retention rate was 75% at 6months. At baseline, 28% and 45% of women met guidelines for intake of fiber and of fruits and vegetables, respectively. After 6months, total serum carotenoid levels and α- and β-carotene concentrations were significantly increased in both groups (P<0.01); however, β-carotene concentrations were increased more in the FVJC group. Serum β-cryptoxanthin levels, fiber intake (+5.2g/day), and daily servings of juice (+0.9 servings/day) and vegetables (+1.3 servings/day) were all significantly increased in the LFHF group (all P<0.05). Serum levels of albumin, lutein and zeaxanthin, retinol, and retinyl palmitate were significantly increased in the FVJC group (all P<0.05). No changes in cancer antigen-125, anthropometry, or HRQOL were observed. CONCLUSION: Overall, this study supports the feasibility of designing dietary interventions for stage II-IV ovarian cancer survivors and provides preliminary evidence that a low fat high fiber diet and a diet supplemented with encapsulated FVJC may increase phytonutrients in ovarian cancer survivors.Keywords ovarian cancer, lifestyle, nutrition, diet, cancer survivors, carotenoids, tocopherols, comparative effectiveness, and randomized study.}, added-at = {2011-12-15T12:40:58.000+0100}, author = {Paxton, Raheem J. and Garcia-Prieto, Celia and Berglund, Maria and Hernandez, Mike and Hejek, Richard A. and Handy, Beverly and Brown, Jubilee and Jones, Lovell A.}, biburl = {https://www.bibsonomy.org/bibtex/2d16f07d7296157c6984436b2c8012c8c/treppenlift}, doi = {10.1016/j.ygyno.2011.11.031}, interhash = {4437a399d1e6f7da4d7ca5d8e7da484d}, intrahash = {d16f07d7296157c6984436b2c8012c8c}, issn = {0090-8258}, journal = {Gynecologic Oncology}, keywords = {}, number = 0, pages = { - }, timestamp = {2011-12-15T12:40:58.000+0100}, title = {A randomized parallel-group dietary study for stage ii-iv ovarian cancer survivors}, url = {http://www.sciencedirect.com/science/article/pii/S0090825811009498}, year = 2011 }