%0 Journal Article %1 Mysliwiec.2009 %A Mysliwiec, P. %A Pawlak, K. %A Bandurski, R. %A Kedra, B. %D 2009 %J Folia Histochem.Cytobiol. %K A Adult Aged Antigens Biological CD Care Case-Control Cell Endothelial Factor Female Growth Human Humans Male Markers Middle Neoplasms Neovascularization Pathologic Plasma Preoperative Receptor-2 Receptors Solubility Stomach Studies Surface Tumor Vascular blood metabolism protein supply surgery %N 1 %P 81-86 %T Soluble angiogenesis markers in gastric tumor patients %U PM:19419943 %V 47 %X Gastric cancer is the second commonest cause of cancer-associated death in the world. Its molecular markers can be useful not only for diagnostic, but also prognostic purposes. The aim of the study was to assess the usefulness of soluble angiogenesis markers such as endoglin and VEGFR2 in gastric cancer patients and to compare these results with those of VEGF levels. As a secondary objective, we compared the concentrations of all three soluble markers in plasma and serum. The study was performed on 26 patients with gastric cancer (17 intestinal-type and 9 diffuse-type), and additionally in 2 patients with B cell lymphoma and 2 with gastro-intestinal stromal tumor. In summary, we showed increases in circulating VEGF-A in patients with both types of gastric cancer. The levels of VEGFR2 did not change significantly in patients with gastric cancer as compared to healthy subjects. Interestingly, after the operation greater levels of VEGFR2 were observed in patients without metastases. Both

@article{Mysliwiec.2009, abstract = {Gastric cancer is the second commonest cause of cancer-associated death in the world. Its molecular markers can be useful not only for diagnostic, but also prognostic purposes. The aim of the study was to assess the usefulness of soluble angiogenesis markers such as endoglin and VEGFR2 in gastric cancer patients and to compare these results with those of VEGF levels. As a secondary objective, we compared the concentrations of all three soluble markers in plasma and serum. The study was performed on 26 patients with gastric cancer (17 intestinal-type and 9 diffuse-type), and additionally in 2 patients with B cell lymphoma and 2 with gastro-intestinal stromal tumor. In summary, we showed increases in circulating VEGF-A in patients with both types of gastric cancer. The levels of VEGFR2 did not change significantly in patients with gastric cancer as compared to healthy subjects. Interestingly, after the operation greater levels of VEGFR2 were observed in patients without metastases. Both }, added-at = {2010-02-05T11:28:39.000+0100}, author = {Mysliwiec, P. and Pawlak, K. and Bandurski, R. and Kedra, B.}, biburl = {https://www.bibsonomy.org/bibtex/2f5390ae2f96164bc857b2848fd34dea4/kanefendt}, interhash = {8c97f1e2ece73e7bfb6fbd1cb0caae7c}, intrahash = {f5390ae2f96164bc857b2848fd34dea4}, journal = {Folia Histochem.Cytobiol.}, keywords = {A Adult Aged Antigens Biological CD Care Case-Control Cell Endothelial Factor Female Growth Human Humans Male Markers Middle Neoplasms Neovascularization Pathologic Plasma Preoperative Receptor-2 Receptors Solubility Stomach Studies Surface Tumor Vascular blood metabolism protein supply surgery}, number = 1, pages = {81-86}, timestamp = {2010-02-05T11:28:53.000+0100}, title = {Soluble angiogenesis markers in gastric tumor patients}, url = {PM:19419943}, volume = 47, year = 2009 }