%0 Journal Article %1 Hutton1994 %A Hutton, J. L. %A Cooke, T. %A Pharoah, P. O. %D 1994 %J BMJ %K Birth Weight; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Disabled Persons; England; Female; Gestational Age; Humans; Intelligence; Life Expectancy; Male; Motor Skills; Movem; Registries; Sex Distribution; Survival Analysis; ent %N 6952 %P 431--435 %T Life expectancy in children with cerebral palsy. %V 309 %X OBJECTIVE--To determine life expectancy of children with cerebral palsy. DESIGN--Cohort analysis, by means of register compiled from multiple sources of ascertainment, of all children with cerebral palsy born during 1966-84 to mothers resident in Mersey region. Status of children was determined by flagging through NHS central register. SUBJECTS--1258 subjects with idiopathic cerebral palsy, of whom 1251 were traced and included in analysis. MAIN OUTCOME MEASURES--Effect of functional ability (ambulation, manual dexterity, and mental ability), sex, birth weight, and gestational age on survival. RESULTS--20 year survival for whole cohort was 89.3\% for females and 86.9\% for males. For subjects with no severe functional disabilities 20 year survival was 99\% (95\% confidence interval 98\% to 100\%), while subjects severely disabled in all three functional groups had 20 year survival of 50\% (42\% to 58\%). Subjects with birth weight < or = 2500 g had 20 year survival of 92\% (89\% to 95\%), while those with birth weight > 2500 g had survival of 87\% (84\% to 89\%). Subjects with gestational age of > 37 weeks had 20 year survival of 93\% (91\% to 96\%), while those with gestational age > or = 37 weeks had survival of 85\% (83\% to 88\%). Birth weight and gestational age were less predictive of survival than functional disability. Best statistical model used gestational age and number of severe functional disabilities as predictors. CONCLUSIONS--Life expectancy of this cohort of children with cerebral palsy was greater than has been suggested in some previous studies. This has important implications for social, educational, and health services.

@article{Hutton1994, abstract = {OBJECTIVE--To determine life expectancy of children with cerebral palsy. DESIGN--Cohort analysis, by means of register compiled from multiple sources of ascertainment, of all children with cerebral palsy born during 1966-84 to mothers resident in Mersey region. Status of children was determined by flagging through NHS central register. SUBJECTS--1258 subjects with idiopathic cerebral palsy, of whom 1251 were traced and included in analysis. MAIN OUTCOME MEASURES--Effect of functional ability (ambulation, manual dexterity, and mental ability), sex, birth weight, and gestational age on survival. RESULTS--20 year survival for whole cohort was 89.3\% for females and 86.9\% for males. For subjects with no severe functional disabilities 20 year survival was 99\% (95\% confidence interval 98\% to 100\%), while subjects severely disabled in all three functional groups had 20 year survival of 50\% (42\% to 58\%). Subjects with birth weight < or = 2500 g had 20 year survival of 92\% (89\% to 95\%), while those with birth weight > 2500 g had survival of 87\% (84\% to 89\%). Subjects with gestational age of > 37 weeks had 20 year survival of 93\% (91\% to 96\%), while those with gestational age > or = 37 weeks had survival of 85\% (83\% to 88\%). Birth weight and gestational age were less predictive of survival than functional disability. Best statistical model used gestational age and number of severe functional disabilities as predictors. CONCLUSIONS--Life expectancy of this cohort of children with cerebral palsy was greater than has been suggested in some previous studies. This has important implications for social, educational, and health services.}, added-at = {2014-07-19T20:29:06.000+0200}, author = {Hutton, J. L. and Cooke, T. and Pharoah, P. O.}, biburl = {https://www.bibsonomy.org/bibtex/22c7735acf3dd4e5b889f1edacf1a47c2/ar0berts}, groups = {public}, interhash = {e6d6b7a37f8f2fc7e008982e97a82080}, intrahash = {2c7735acf3dd4e5b889f1edacf1a47c2}, journal = {BMJ}, keywords = {Birth Weight; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Disabled Persons; England; Female; Gestational Age; Humans; Intelligence; Life Expectancy; Male; Motor Skills; Movem; Registries; Sex Distribution; Survival Analysis; ent}, month = Aug, number = 6952, pages = {431--435}, pmid = {7920125}, timestamp = {2014-07-19T20:29:06.000+0200}, title = {Life expectancy in children with cerebral palsy.}, username = {ar0berts}, volume = 309, year = 1994 }