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Response to the comment by Wolf Ihlenfeldt on the paper "Indexing molecules with chemical graph identifiers"., , and . J. Comput. Chem., 33 (2): 238 (2012)Chemoisosterism in the Proteome., and . Journal of Chemical Information and Modeling, 53 (2): 279-292 (2013)Illuminating the Chemical Space of Untargeted Proteins., and . J. Chem. Inf. Model., 63 (9): 2689-2698 (May 2023)A molecular-field-based similarity study of non-nucleoside HIV-1 reverse transcriptase inhibitors. 2. The relationship between alignment solutions obtained from conformationally rigid and flexible matching., , and . J. Comput. Aided Mol. Des., 14 (1): 39-51 (2000)A molecular-field-based similarity study of non-nucleoside HIV-1 reverse transcriptase inhibitors., , and . J. Comput. Aided Mol. Des., 13 (1): 79-93 (1999)FCP: functional coverage of the proteome by structures., , and . Bioinform., 22 (14): 1792-1793 (2006)Genetic Algorithms: A Robust Scheme for Geometry Optimizations and Global Minimum Structure Problems., and . J. Comput. Chem., 16 (6): 729-742 (1995)A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research., , , , , , , , , and 9 other author(s). J. Chem. Inf. Model., 62 (3): 718-729 (2022)Identification of the Core Chemical Structure in SureChEMBL Patents., and . J. Chem. Inf. Model., 61 (5): 2241-2247 (2021)Prediction of the P. falciparum Target Space Relevant to Malaria Drug Discovery., and . PLoS Comput. Biol., (2013)