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Divalent metal ions Mg2+ and Ca2+ have distinct effects on protein kinase A activity and regulation

, , , , , , and . ACS Chemical Biology, 10 (10): 2303-2315 (2015)
DOI: 10.1021/acschembio.5b00271

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Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase, , , and . Biochemistry, (1999)Protein kinase Structure and Function: cAMP-dependent Protein Kinase, , , , , , , and . Cellular Regulation by Protein Phosphorylation, 56, Springer, (1991)Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formation, , , , and . Biochemistry, (1994)Physiological inhibitors of the catalytic subunit of cAMP-dependent protein kinase: effect of MgATP on protein-protein interactions, and . Biochemistry, (1993)Expression of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli: multiple isozymes reflect different phosphorylation states, , and . Protein Eng, (1993)UTILIZATION OF FUSION SYSTEMS AND PROTEIN-PROTEIN INTERACTIONS FOR PRODUCTION AND PURIFICATION OF MUTANT SUBUNITS OF CAMP-DEPENDENT PROTEIN-KINASE, , , and . 8, page A1226. (April 1994)MUTANTS OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN-KINASE THAT ARE DEFECTIVE IN RECOGNITION OF THE HEAT-STABLE PROTEIN-KINASE INHIBITOR, , and . 7, page A1122. (April 1993)BIOCHEMICAL-PROPERTIES OF A MONOMERIC REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN-KINASE, , and . 7, page A1122. (April 1993)Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains, , , , , , , and . Science, 269 (5225): 807-813 (August 1995)cAMP-dependent protein kinase defines a family of enzymes, , , , , , , and . Philos Trans R Soc Lond B Biol Sci, 340 (1293): 315-324 (June 1993)