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Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

F. Couch, X. Wang, L. McGuffog, A. Lee, C. Olswold, K. Kuchenbaecker, P. Soucy, Z. Fredericksen, D. Barrowdale, J. Dennis, M. Gaudet, E. Dicks, M. Kosel, S. Healey, O. Sinilnikova, A. Lee, F. Bacot, D. Vincent, Hogervorst, Frans B L, S. Peock, D. Stoppa-Lyonnet, A. Jakubowska, P. Radice, R. Schmutzler, S. Domchek, M. Piedmonte, C. Singer, E. Friedman, M. Thomassen, Hansen, Thomas V O, S. Neuhausen, C. Szabo, I. Blanco, M. Greene, B. Karlan, J. Garber, C. Phelan, J. Weitzel, M. Montagna, E. Olah, I. Andrulis, A. Godwin, D. Yannoukakos, D. Goldgar, T. Caldes, H. Nevanlinna, A. Osorio, M. Terry, M. Daly, van Rensburg, Elizabeth J, U. Hamann, S. Ramus, A. Toland, M. Caligo, O. Olopade, N. Tung, K. Claes, M. Beattie, M. Southey, E. Imyanitov, M. Tischkowitz, R. Janavicius, E. John, A. Kwong, O. Diez, J. Balmaña, R. Barkardottir, B. Arun, G. Rennert, S. Teo, P. Ganz, I. Campbell, van der Hout, Annemarie H, van Deurzen, Carolien H M, C. Seynaeve, Gómez Garcia, Encarna B, van Leeuwen, Flora E, Meijers-Heijboer, Hanne E J, Gille, Johannes J P, Ausems, Margreet G E M, M. Blok, Ligtenberg, Marjolijn J L, M. Rookus, P. Devilee, S. Verhoef, van Os, Theo A M, J. Wijnen, D. Frost, S. Ellis, E. Fineberg, R. Platte, D. Evans, L. Izatt, R. Eeles, J. Adlard, D. Eccles, J. Cook, C. Brewer, F. Douglas, S. Hodgson, P. Morrison, L. Side, A. Donaldson, C. Houghton, M. Rogers, H. Dorkins, J. Eason, H. Gregory, E. McCann, A. Murray, A. Calender, A. Hardouin, P. Berthet, C. Delnatte, C. Nogues, C. Lasset, C. Houdayer, D. Leroux, E. Rouleau, F. Prieur, F. Damiola, H. Sobol, I. Coupier, L. Venat-Bouvet, L. Castera, M. Gauthier-Villars, M. Léoné, P. Pujol, S. Mazoyer, Y. Bignon, E. Złowocka-Perłowska, J. Gronwald, J. Lubinski, K. Durda, K. Jaworska, T. Huzarski, A. Spurdle, A. Viel, B. Peissel, B. Bonanni, G. Melloni, L. Ottini, L. Papi, L. Varesco, M. Tibiletti, P. Peterlongo, S. Volorio, S. Manoukian, V. Pensotti, N. Arnold, C. Engel, H. Deissler, D. Gadzicki, A. Gehrig, K. Kast, K. Rhiem, A. Meindl, D. Niederacher, N. Ditsch, H. Plendl, S. Preisler-Adams, S. Engert, C. Sutter, R. Varon-Mateeva, B. Wappenschmidt, Weber, Bernhard H F, B. Arver, M. Stenmark-Askmalm, N. Loman, R. Rosenquist, Z. Einbeigi, K. Nathanson, T. Rebbeck, S. Blank, D. Cohn, G. Rodriguez, L. Small, M. Friedlander, V. Bae-Jump, A. Fink-Retter, C. Rappaport, D. Gschwantler-Kaulich, G. Pfeiler, M. Tea, N. Lindor, B. Kaufman, S. Shimon Paluch, Y. Laitman, A. Skytte, A. Gerdes, I. Pedersen, S. Moeller, T. Kruse, U. Jensen, J. Vijai, K. Sarrel, M. Robson, N. Kauff, A. Mulligan, G. Glendon, H. Ozcelik, B. Ejlertsen, F. Nielsen, L. Jønson, M. Andersen, Y. Ding, L. Steele, L. Foretova, A. Teulé, C. Lazaro, J. Brunet, M. Pujana, P. Mai, J. Loud, C. Walsh, J. Lester, S. Orsulic, S. Narod, J. Herzog, S. Sand, S. Tognazzo, S. Agata, T. Vaszko, J. Weaver, A. Stavropoulou, S. Buys, A. Romero, de la Hoya, Miguel, K. Aittomäki, T. Muranen, M. Duran, W. Chung, A. Lasa, C. Dorfling, A. Miron, J. Benitez, L. Senter, D. Huo, S. Chan, A. Sokolenko, J. Chiquette, L. Tihomirova, T. Friebel, B. Agnarsson, K. Lu, F. Lejbkowicz, P. James, P. Hall, A. Dunning, D. Tessier, J. Cunningham, S. Slager, C. Wang, S. Hart, K. Stevens, J. Simard, T. Pastinen, V. Pankratz, K. Offit, D. Easton, G. Chenevix-Trench, и A. Antoniou. PLoS genetics, 9 (3): e1003212 (2013)

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Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriersD. Cox, J. Simard, D. Sinnett, Y. Hamdi, P. Soucy, M. Ouimet, L. Barjhoux, C. Verny-Pierre, L. McGuffog, S. Healey и 99 other автор(ы). Human molecular genetics, 20 (23): 4732–4747 (2011)Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriersA. Antoniou, C. Kartsonaki, O. Sinilnikova, P. Soucy, L. McGuffog, S. Healey, A. Lee, P. Peterlongo, S. Manoukian, B. Peissel и 169 other автор(ы). Human molecular genetics, 20 (16): 3304–3321 (2011)A Growth Curve Model with Fractional Polynomials for Analysing Incomplete Time-Course Data in Microarray Gene Expression Studies.Q. Tan, M. Thomassen, J. v. B. Hjelmborg, A. Clemmensen, K. Andersen, T. Petersen, M. McGue, K. Christensen, и T. Kruse. Adv. Bioinformatics, (2011)Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)N. Mavaddat, D. Barrowdale, I. Andrulis, S. Domchek, D. Eccles, H. Nevanlinna, S. Ramus, A. Spurdle, M. Robson, M. Sherman и 123 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 (1): 134–147 (2012)Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriersF. Couch, M. Gaudet, A. Antoniou, S. Ramus, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, X. Wang, T. Kirchhoff и 180 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 (4): 645–657 (2012)Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerS. Bojesen, K. Pooley, S. Johnatty, J. Beesley, K. Michailidou, J. Tyrer, S. Edwards, H. Pickett, H. Shen, C. Smart и 427 other автор(ы). Nature genetics, 45 (4): 371-84, 384e1-2 (2013)Gene Selection for Predicting Survival Outcomes of Cancer Patients in Microarray Studies.Q. Tan, M. Thomassen, K. Jochumsen, O. Mogensen, K. Christensen, и T. Kruse. SCSS (1), стр. 405-409. Springer, (2007)Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskF. Couch, X. Wang, L. McGuffog, A. Lee, C. Olswold, K. Kuchenbaecker, P. Soucy, Z. Fredericksen, D. Barrowdale, J. Dennis и 252 other автор(ы). PLoS genetics, 9 (3): e1003212 (2013)Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2A. Mulligan, F. Couch, D. Barrowdale, S. Domchek, D. Eccles, H. Nevanlinna, S. Ramus, M. Robson, M. Sherman, A. Spurdle и 172 other автор(ы). Breast cancer research : BCR, 13 (6): R110 (2011)Latent growth curve modeling of incomplete timecourse data in microarray gene expression studies.Q. Tan, M. Thomassen, и T. Kruse. CIBCB, стр. 100-104. IEEE, (2012)

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