The Django REST interface makes it easy to offer private and public APIs for existing Django models. New generic views simplify data retrieval and modification in a resource-centric architecture and provide model data in formats such as XML, JSON and YAML with very little custom code.
PyFacebook is currently best-tested with Django, and if you are just starting out with Python web development, the author highly recommends this combination :-). If you'd rather use another framework, there are also Pylons and other WSGI helpers in PyFacebook as well.
The Django REST interface makes it easy to offer private and public APIs for existing Django models. New generic views simplify data retrieval and modification in a resource-centric architecture