Аннотация
NeisVac-C has been demonstrated to be safe, immunogenic and efficacious when administered to infants, toddlers, older children and adults. It is one of the licensed meningococcal serogroup C conjugate vaccines and a single dose in infancy may be sufficient for protection until a booster dose is given in the second year of life. Persistence of serum bactericidal antibody, rather than immune memory, is now known to be a more appropriate correlate of long-term protection for serogroup C meningococcal disease. NeisVac-C was demonstrated to enhance responses to Haemophilus influenzae type b (Hib) polyribosylribitol phosphate when coadministered with Hib-tetanus toxoid conjugate vaccines. NeisVac-C also enhances tetanus toxid responses and a dose of NeisVac-C in older children induces responses similar to a dose of tetanus toxoid vaccine.
- adolescent,
- adult
- adult,
- aged,
- antibodies,
- bacterial,
- child,
- conjugate,
- haemophilus
- humans,
- immunologic
- infant,
- memory,
- meningitis,
- meningococcal
- meningococcal,
- middle
- preschool,
- tetanus
- toxoid,
- vaccines,
- young
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